ATXN10 Antibody - #DF9231
| 製品: | ATXN10 Antibody |
| カタログ: | DF9231 |
| タンパク質の説明: | Rabbit polyclonal antibody to ATXN10 |
| アプリケーション: | WB |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Rabbit, Dog |
| 分子量: | 53kDa; 53kD(Calculated). |
| ユニプロット: | Q9UBB4 |
| RRID: | AB_2842427 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF9231, RRID:AB_2842427.
折りたたみ／展開
Ataxin 10; Ataxin-10; ATX10_HUMAN; Atxn10; Brain protein E46 homolog; E46L; FLJ37990; HUMEEP; Like mouse brain protein E46; OTTHUMP00000197383; SCA10; Spinocerebellar ataxia 10; Spinocerebellar ataxia type 10 protein;
免疫原
- Q9UBB4 ATX10_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAPRPPPARLSGVMVPAPIQDLEALRALTALFKEQRNRETAPRTIFQRVLDILKKSSHAVELACRDPSQVENLASSLQLITECFRCLRNACIECSVNQNSIRNLDTIGVAVDLILLFRELRVEQESLLTAFRCGLQFLGNIASRNEDSQSIVWVHAFPELFLSCLNHPDKKIVAYSSMILFTSLNHERMKELEENLNIAIDVIDAYQKHPESEWPFLIITDLFLKSPELVQAMFPKLNNQERVTLLDLMIAKITSDEPLTKDDIPVFLRHAELIASTFVDQCKTVLKLASEEPPDDEEALATIRLLDVLCEMTVNTELLGYLQVFPGLLERVIDLLRVIHVAGKETTNIFSNCGCVRAEGDISNVANGFKSHLIRLIGNLCYKNKDNQDKVNELDGIPLILDNCNISDSNPFLTQWVIYAIRNLTEDNSQNQDLIAKMEEQGLADASLLKKVGFEVEKKGEKLILKSTRDTPKP
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9UBB4 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| R5 | Methylation | Uniprot | |
| R10 | Methylation | Uniprot | |
| S12 | Phosphorylation | Q96GD4 (AURKB) | Uniprot |
| T30 | Phosphorylation | Uniprot | |
| K34 | Acetylation | Uniprot | |
| K34 | Ubiquitination | Uniprot | |
| K56 | Ubiquitination | Uniprot | |
| S77 | Phosphorylation | P53350 (PLK1) | Uniprot |
| T82 | Phosphorylation | P53350 (PLK1) | Uniprot |
| T221 | Phosphorylation | Uniprot | |
| K237 | Ubiquitination | Uniprot | |
| K262 | Ubiquitination | Uniprot | |
| C283 | S-Nitrosylation | Uniprot | |
| K284 | Ubiquitination | Uniprot | |
| K288 | Ubiquitination | Uniprot | |
| K345 | Ubiquitination | Uniprot | |
| S364 | Phosphorylation | Uniprot | |
| K371 | Ubiquitination | Uniprot | |
| K384 | Ubiquitination | Uniprot | |
| T426 | Phosphorylation | Uniprot | |
| S430 | Phosphorylation | Uniprot | |
| K438 | Ubiquitination | Uniprot | |
| S448 | Phosphorylation | Uniprot | |
| K451 | Ubiquitination | Uniprot | |
| K452 | Ubiquitination | Uniprot | |
| K459 | Ubiquitination | Uniprot | |
| K467 | Ubiquitination | Uniprot |
研究背景
Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis.
Cytoplasm>Perinuclear region.
Expressed in the central nervous system.
Homooligomer (By similarity). Interacts with OGT (By similarity). Interacts with GNB2. Interacts with IQCB1.
Belongs to the ataxin-10 family.
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