PLCH Antibody - #AF0485
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF0485, RRID:AB_2834275.
折りたたみ／展開
1 acylglycerol 3 phosphate O acyltransferase 8; 1 acylglycerol 3 phosphate O acyltransferase 9; 1 AGP acyltransferase 9; 1 AGPAT 9; 1-acylglycerol-3-phosphate O-acyltransferase 9; 1-AGP acyltransferase 9; 1-AGPAT 9; Acyl CoA:glycerol 3 phosphate acyltransferase 3; Acyl-CoA:glycerol-3-phosphate acyltransferase 3; AGPAT8; AGPAT9; Endoplasmic reticulum associated GPAT; Glycerol-3-phosphate acyltransferase 3; GPAT-3; GPAT3; GPAT3_HUMAN; hGPAT3; HMFN0839; LPAAT theta; LPAAT-theta; Lung cancer metastasis associated protein; Lung cancer metastasis-associated protein 1; Lysophosphatidic acid acyltransferase theta; MAG 1; MAG-1; MGC11324; PLCH;
免疫原
Widely expressed. Expressed in liver, kidney, testis, brain, heart, skeletal muscle, thyroid, prostate, thymus and placenta. Also expressed lung and adipose tissue.
- Q53EU6 GPAT3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEGAELAGKILSTWLTLVLGFILLPSVFGVSLGISEIYMKILVKTLEWATIRIEKGTPKESILKNSASVGIIQRDESPMEKGLSGLRGRDFELSDVFYFSKKGLEAIVEDEVTQRFSSEELVSWNLLTRTNVNFQYISLRLTMVWVLGVIVRYCVLLPLRVTLAFIGISLLVIGTTLVGQLPDSSLKNWLSELVHLTCCRICVRALSGTIHYHNKQYRPQKGGICVANHTSPIDVLILTTDGCYAMVGQVHGGLMGIIQRAMVKACPHVWFERSEMKDRHLVTKRLKEHIADKKKLPILIFPEGTCINNTSVMMFKKGSFEIGGTIHPVAIKYNPQFGDAFWNSSKYNMVSYLLRMMTSWAIVCDVWYMPPMTREEGEDAVQFANRVKSAIAIQGGLTELPWDGGLKRAKVKDIFKEEQQKNYSKMIVGNGSLS
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q53EU6 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K59 | Ubiquitination | Uniprot | |
| K64 | Ubiquitination | Uniprot | |
| S66 | Phosphorylation | Uniprot | |
| S68 | Phosphorylation | Uniprot | |
| S77 | Phosphorylation | Uniprot | |
| K81 | Ubiquitination | Uniprot | |
| K102 | Ubiquitination | Uniprot | |
| K264 | Ubiquitination | Uniprot | |
| K284 | Acetylation | Uniprot | |
| K316 | Acetylation | Uniprot | |
| Y347 | Phosphorylation | Uniprot | |
| Y352 | Phosphorylation | Uniprot | |
| K388 | Ubiquitination | Uniprot | |
| K407 | Acetylation | Uniprot | |
| K407 | Ubiquitination | Uniprot | |
| S434 | Phosphorylation | Uniprot |
研究背景
Converts glycerol-3-phosphate to 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) by incorporating an acyl moiety at the sn-1 position of the glycerol backbone. Also converts LPA into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
Endoplasmic reticulum membrane>Multi-pass membrane protein.
Widely expressed. Expressed in liver, kidney, testis, brain, heart, skeletal muscle, thyroid, prostate, thymus and placenta. Also expressed lung and adipose tissue.
The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
研究領域
· Metabolism > Lipid metabolism > Glycerolipid metabolism.
· Metabolism > Lipid metabolism > Glycerophospholipid metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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