製品: UBXD5 Antibody
カタログ: AF0606
タンパク質の説明: Rabbit polyclonal antibody to UBXD5
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Sheep, Rabbit
分子量: 57kDa; 57kD(Calculated).
ユニプロット: Q5T124
RRID: AB_2834280

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(86%), Bovine(100%), Sheep(100%), Rabbit(88%)
クローナリティ:
Polyclonal
特異性:
UBXD5 Antibody detects endogenous levels of total UBXD5.
RRID:
AB_2834280
引用形式: Affinity Biosciences Cat# AF0606, RRID:AB_2834280.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

COA 1; colorectal tumor associated antigen 1; Colorectal tumor associated antigen COA 1; PP2243; SOC; SOCI; Socius; UBX domain containing 5; UBX domain containing protein 11; UBX domain containing protein 5; UBXD 5; UBXN11;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質の説明:
UBXN11 May be involved in the reorganization of actin cytoskeleton mediated by RND1, RND2 AND RND3. Promotes RHOA activation mediated by GNA12 and GNA13. Interacts with GNA12, GNA13, RND1, RND2 AND RND3. 8 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
タンパク質配列:
MSSPLASLSKTRKVPLPSEPMNPGRRGIRIYGDEDEVDMLSDGCGSEEKISVPSCYGGIGAPVSRQVPASHDSELMAFMTRKLWDLEQQVKAQTDEILSKDQKIAALEDLVQTLRPHPAEATLQRQEELETMCVQLQRQVREMERFLSDYGLQWVGEPMDQEDSESKTVSEHGERDWMTAKKFWKPGDSLAPPEVDFDRLLASLQDLSELVVEGDTQVTPVPGGARLRTLEPIPLKLYRNGIMMFDGPFQPFYDPSTQRCLRDILDGFFPSELQRLYPNGVPFKVSDLRNQVYLEDGLDPFPGEGRVVGRQLMHKALDRVEEHPGSRMTAEKFLNRLPKFVIRQGEVIDIRGPIRDTLQNCCPLPARIQEIVVETPTLAAERERSQESPNTPAPPLSMLRIKSENGEQAFLLMMQPDNTIGDVRALLAQARVMDASAFEIFSTFPPTLYQDDTLTLQAAGLVPKAALLLRARRAPKSSLKFSPGPCPGPGPGPSPGPGPGPSPGPGPGPSPCPGPSPSPQ

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Bovine
100
Sheep
100
Rabbit
88
Pig
86
Horse
78
Dog
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q5T124 基板として

Site PTM Type Enzyme
S3 Phosphorylation
S9 Phosphorylation
K13 Ubiquitination
S70 Phosphorylation
S73 Phosphorylation
T80 Phosphorylation
K100 Ubiquitination
S208 Phosphorylation
K236 Ubiquitination
K284 Ubiquitination
K402 Ubiquitination

研究背景

機能:

May be involved in the reorganization of actin cytoskeleton mediated by RND1, RND2 AND RND3. Promotes RHOA activation mediated by GNA12 and GNA13 (By similarity).

細胞の位置付け:

Cytoplasm>Cytoskeleton.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Interacts with GNA12, GNA13, RND1, RND2 AND RND3.

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