製品: TTC23 Antibody
カタログ: AF0706
タンパク質の説明: Rabbit polyclonal antibody to TTC23
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse
予測: Pig, Bovine, Horse, Sheep, Dog
分子量: 50kDa; 50kD(Calculated).
ユニプロット: Q5W5X9
RRID: AB_2834283

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製品説明

ソース:
Rabbit
アプリケーション:
IHC 1:50-1:200, WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
予測:
Pig(91%), Bovine(91%), Horse(91%), Sheep(91%), Dog(90%)
クローナリティ:
Polyclonal
特異性:
TTC23 Antibody detects endogenous levels of total TTC23.
RRID:
AB_2834283
引用形式: Affinity Biosciences Cat# AF0706, RRID:AB_2834283.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Cervical cancer proto oncogene 8 protein; Cervical cancer proto-oncogene 8 protein; HCC 8; HCC-8; OTTHUMP00000190851; Protooncogene 8; Tetratricopeptide repeat domain 23; Tetratricopeptide repeat protein 23; TPR repeat protein 23; Ttc23; TTC23_HUMAN;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質の説明:
TTC23 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
タンパク質配列:
MQESQETHISNHLDEVVAAVSITHRKKFQNKLLQTALFQPPREKLHLCEEKAKSYSNSHEYKQAVHELVRCVALTRICYGDSHWKLAEAHVNLAQGYLQLKGLSLQAKQHAEKARQILANSIVPPYSENTDVFKFSIELFHTMGRALLSLQKFKEAAENLTKAERLSKELLQCGRIIKEEWIEIEARIRLSFAQVYQGQKKSKEALSHYQAALEYVEISKGETSRECVPILRELAGVEQALGLHDVSINHFLQAHLIILSRSPSQVEAADSAHIVAHAAVASGRHEHHDVAEQYFQESMAHLKDSEGMGRTKFLSIQDEFCHFLQMTGQKERATSILRESLEAKVEAFGDFSPEVAETYRLLGGADLAQGNHSGARKKLKKCLQIQTLLYGPQDKRTLATQQAMGMLSTAPKVASKPRQASKAKVAFCTSIPQDTLLGKARPGTTAD

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
91
Horse
91
Bovine
91
Sheep
91
Dog
90
Rabbit
73
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q5W5X9 基板として

Site PTM Type Enzyme
T161 Phosphorylation
S167 Phosphorylation
S415 Phosphorylation

研究背景

機能:

Participates positively in the ciliary Hedgehog (Hh) signaling.

細胞の位置付け:

Cell projection>Cilium.
Note: Colocalizes with EVC and IQCE at the EvC zone of primary cilia.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Found Associated with the EvC complex composed of EFCAB7, IQCE, EVC2 and EVC.

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