ATPBD3 Antibody - #AF0721
| 製品: | ATPBD3 Antibody |
| カタログ: | AF0721 |
| タンパク質の説明: | Rabbit polyclonal antibody to ATPBD3 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human |
| 予測: | Pig, Bovine |
| 分子量: | 36~43kDa; 36kD(Calculated). |
| ユニプロット: | Q7Z7A3 |
| RRID: | AB_2834295 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF0721, RRID:AB_2834295.
折りたたみ／展開
ATP binding domain 3; ATP-binding domain-containing protein 3; Cancer associated protein; Cancer-associated gene protein; ctu1; CTU1_HUMAN; Cytoplasmic tRNA 2-thiolation protein 1; Cytoplasmic tRNA adenylyltransferase 1; Cytosolic thiouridylase subunit 1 homolog; NCS6;
免疫原
- Q7Z7A3 CTU1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPAPPCASCHAARAALRRPLSGQALCGACFCAAFEAEVLHTVLAGRLLPPGAVVAVGASGGKDSTVLAHVLRALAPRLGISLQLVAVDEGIGGYRDAALAAVRRQAARWELPLTVVAYEDLFGGWTMDAVARSTAGSGRSRSCCTFCGVLRRRALEEGARRVGATHIVTGHNADDMAETVLMNFLRGDAGRLARGGGLGSPGEGGALPRCRPLQFASQKEVVLYAHFRRLDYFSEECVYAPEAFRGHARDLLKRLEAARPSAVLDLVHSAERLALAPAARPPRPGACSRCGALASRALCQACALLDGLNRGRPRLAIGKGRRGLDEEATPGTPGDPARPPASKAVPTF
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q7Z7A3 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S81 | Phosphorylation | Uniprot | |
| Y94 | Phosphorylation | Uniprot | |
| S142 | Phosphorylation | Uniprot | |
| T145 | Phosphorylation | Uniprot | |
| R194 | Methylation | Uniprot | |
| S200 | Phosphorylation | Uniprot | |
| S234 | Phosphorylation | Uniprot | |
| K319 | Ubiquitination | Uniprot | |
| T329 | Phosphorylation | Uniprot | |
| T332 | Phosphorylation | Uniprot | |
| K343 | Ubiquitination | Uniprot |
研究背景
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
Cytoplasm.
Component of a complex at least composed of URM1, CTU2/NCS2 and CTU1/ATPBD3. May form a heterodimer with CTU2/NCS2.
Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
研究領域
· Genetic Information Processing > Folding, sorting and degradation > Sulfur relay system. (View pathway)
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