Phospho-KIF1C (Ser1092) Antibody - #AF8091

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製品: Phospho-KIF1C (Ser1092) Antibody
カタログ: AF8091
タンパク質の説明: Rabbit polyclonal antibody to Phospho-KIF1C (Ser1092)
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Horse, Sheep, Rabbit, Dog
分子量: 120~150kD; 123kD(Calculated).
ユニプロット: O43896
RRID: AB_2840154

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MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%)
クローナリティ:
Polyclonal
特異性:
Phospho-KIF1C (Ser1092) Antibody detects endogenous levels of KIF1C only when phosphorylated at Ser1092.
RRID:
AB_2840154
引用形式: Affinity Biosciences Cat# AF8091, RRID:AB_2840154.
コンジュゲート:
Unconjugated.
精製:
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

Kif1c; KIF1C_HUMAN; Kinesin family member 1C; Kinesin-like protein KIF1C; LTXS1;

免疫原

免疫原:
Uniprot:

O43896(KIF1C_HUMAN) >>Visit HPA database.

遺伝子(ID):
KIF1C(10749)
発現特異性:
O43896 KIF1C_HUMAN:

Expressed in all tissues examined, with most abundant expression in heart and skeletal muscle.

タンパク質配列:
MAGASVKVAVRVRPFNARETSQDAKCVVSMQGNTTSIINPKQSKDAPKSFTFDYSYWSHTSTEDPQFASQQQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGRQEPGQQGIVPQLCEDLFSRVSENQSAQLSYSVEVSYMEIYCERVRDLLNPKSRGSLRVREHPILGPYVQDLSKLAVTSYADIADLMDCGNKARTVAATNMNETSSRSHAVFTIVFTQRCHDQLTGLDSEKVSKISLVDLAGSERADSSGARGMRLKEGANINKSLTTLGKVISALADMQSKKRKSDFIPYRDSVLTWLLKENLGGNSRTAMIAALSPADINYEETLSTLRYADRTKQIRCNAIINEDPNARLIRELQEEVARLRELLMAQGLSASALEGLKTEEGSVRGALPAVSSPPAPVSPSSPTTHNGELEPSFSPNTESQIGPEEAMERLQETEKIIAELNETWEEKLRKTEALRMEREALLAEMGVAVREDGGTVGVFSPKKTPHLVNLNEDPLMSECLLYHIKDGVTRVGQVDMDIKLTGQFIREQHCLFRSIPQPDGEVVVTLEPCEGAETYVNGKLVTEPLVLKSGNRIVMGKNHVFRFNHPEQARLERERGVPPPPGPPSEPVDWNFAQKELLEQQGIDIKLEMEKRLQDLENQYRKEKEEADLLLEQQRLYADSDSGDDSDKRSCEESWRLISSLREQLPPTTVQTIVKRCGLPSSGKRRAPRRVYQIPQRRRLQGKDPRWATMADLKMQAVKEICYEVALADFRHGRAEIEALAALKMRELCRTYGKPDGPGDAWRAVARDVWDTVGEEEGGGAGSGGGSEEGARGAEVEDLRAHIDKLTGILQEVKLQNSSKDRELQALRDRMLRMERVIPLAQDHEDENEEGGEVPWAPPEGSEAAEEAAPSDRMPSARPPSPPLSSWERVSRLMEEDPAFRRGRLRWLKQEQLRLQGLQGSGGRGGGLRRPPARFVPPHDCKLRFPFKSNPQHRESWPGMGSGEAPTPLQPPEEVTPHPATPARRPPSPRRSHHPRRNSLDGGGRSRGAGSAQPEPQHFQPKKHNSYPQPPQPYPAQRPPGPRYPPYTTPPRMRRQRSAPDLKESGAAV

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Rabbit
100
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O43896 基板として

Site PTM Type Enzyme
S162 Phosphorylation
T222 Phosphorylation
K243 Ubiquitination
S257 Phosphorylation
S258 Phosphorylation
K266 Ubiquitination
S274 Phosphorylation
T276 Phosphorylation
T277 Phosphorylation
S295 Phosphorylation
S326 Phosphorylation
Y332 Phosphorylation
S385 Phosphorylation
S412 Phosphorylation
T489 Phosphorylation
S494 Phosphorylation
K658 Ubiquitination
Y671 Phosphorylation
S674 Phosphorylation
S676 Phosphorylation
S680 Phosphorylation
T702 Phosphorylation
T703 Phosphorylation
Y726 Phosphorylation
K788 Ubiquitination
S817 Phosphorylation
K839 Ubiquitination
K848 Ubiquitination
S915 Phosphorylation
S919 Phosphorylation
R948 Methylation
S955 Phosphorylation
R958 Methylation
R963 Methylation
S996 Phosphorylation
S1022 Phosphorylation
S1033 Phosphorylation
R1041 Methylation
K1057 Methylation
R1072 Methylation
R1077 Methylation
Y1078 Phosphorylation
Y1081 Phosphorylation
T1082 Phosphorylation
T1083 Phosphorylation
S1092 Phosphorylation P68400 (CSNK2A1) , P19784 (CSNK2A2)

研究背景

機能:

Motor required for the retrograde transport of Golgi vesicles to the endoplasmic reticulum. Has a microtubule plus end-directed motility.

PTMs:

Phosphorylated on tyrosine residues.

細胞の位置付け:

Cytoplasm>Cytoskeleton.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in all tissues examined, with most abundant expression in heart and skeletal muscle.

サブユニット構造:

Monomer. Interacts with BICD2.

タンパク質ファミリー:

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Unc-104 subfamily.

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