製品: C1orf57 Antibody
カタログ: AF0448
タンパク質の説明: Rabbit polyclonal antibody to C1orf57
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse
予測: Bovine, Horse, Sheep, Rabbit
分子量: 21kDa; 21kD(Calculated).
ユニプロット: Q9BSD7
RRID: AB_2834309

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
予測:
Bovine(92%), Horse(92%), Sheep(92%), Rabbit(92%)
クローナリティ:
Polyclonal
特異性:
C1orf57 Antibody detects endogenous levels of total C1orf57.
RRID:
AB_2834309
引用形式: Affinity Biosciences Cat# AF0448, RRID:AB_2834309.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Chromosome 1 open reading frame 57; FLJ11383; HCR NTPase; Human cancer related NTPase; Hypothetical protein LOC84284; MGC13186; Novel DUF829 domain containing protein; Nucleoside triphosphatase C1orf57; Nucleoside triphosphatase, cancer related; Nucleoside triphosphate phosphohydrolase; OTTHUMP00000035941; OTTHUMP00000035942; Probable UPF0334 kinase like protein C1orf57; RP4 659I19.2; RP4 678E16.2;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質の説明:
C1orf57 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. Hydrolyzes nucleoside diphosphates with lower efficiency. Belongs to the THEP1 NTPase family. Monomer.
タンパク質配列:
MARHVFLTGPPGVGKTTLIHKASEVLKSSGVPVDGFYTEEVRQGGRRIGFDVVTLSGTRGPLSRVGLEPPPGKRECRVGQYVVDLTSFEQLALPVLRNADCSSGPGQRVCVIDEIGKMELFSQLFIQAVRQTLSTPGTIILGTIPVPKGKPLALVEEIRNRKDVKVFNVTKENRNHLLPDIVTCVQSSRK

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Horse
92
Bovine
92
Sheep
92
Rabbit
92
Pig
75
Zebrafish
70
Chicken
67
Dog
0
Xenopus
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9BSD7 基板として

Site PTM Type Enzyme
A2 Acetylation
T8 Phosphorylation
K15 Ubiquitination
K21 Acetylation
K21 Ubiquitination
K27 Ubiquitination
Y37 Phosphorylation
T38 Phosphorylation
T54 Phosphorylation
S56 Phosphorylation
K73 Ubiquitination
K150 Ubiquitination
K165 Acetylation
K165 Ubiquitination
T170 Phosphorylation
K171 Ubiquitination

研究背景

機能:

Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. Hydrolyzes nucleoside diphosphates with lower efficiency.

サブユニット構造:

Monomer.

タンパク質ファミリー:

Belongs to the THEP1 NTPase family.

研究領域

· Metabolism > Nucleotide metabolism > Purine metabolism.

· Metabolism > Metabolism of cofactors and vitamins > Thiamine metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

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