Phospho-BORA (Ser497) Antibody - #AF8249
(1)
| 製品: | Phospho-BORA (Ser497) Antibody |
| カタログ: | AF8249 |
| タンパク質の説明: | Rabbit polyclonal antibody to Phospho-BORA (Ser497) |
| アプリケーション: | WB |
| 反応性: | Human, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Chicken, Xenopus |
| 分子量: | 61kDa; 61kD(Calculated). |
| ユニプロット: | Q6PGQ7 |
| RRID: | AB_2840311 |
製品説明
ソース:
Rabbit
アプリケーション:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
反応性:
Human,Rat
予測:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(89%), Chicken(89%), Xenopus(89%)
クローナリティ:
Polyclonal
特異性:
Phospho-BORA (Ser497) Antibody detects endogenous levels of BORA only when phosphorylated at Ser497.
RRID:
AB_2840311
引用形式: Affinity Biosciences Cat# AF8249, RRID:AB_2840311.
引用形式: Affinity Biosciences Cat# AF8249, RRID:AB_2840311.
コンジュゲート:
Unconjugated.
精製:
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:
折りたたみ／展開
Aurora borealis; bora; bora, aurora kinase A activator; BORA_HUMAN; C13orf34; Chromosome 13 open reading frame 34; FLJ22624; HsBora; Protein aurora borealis; RP11-342J4.2;
免疫原
免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
- Q6PGQ7 BORA_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGDVKESKMQITPETPGRIPVLNPFESPSDYSNLHEQTLASPSVFKSTKLPTPGKFRWSIDQLAVINPVEIDPEDIHRQALYLSHSRIDKDVEDKRQKAIEEFFTKDVIVPSPWTDHEGKQLSQCHSSKCTNINSDSPVGKKLTIHSEKSDAACQTLLSLPVDFNLENILGDYFRADEFADQSPGNLSSSSLRRKLFLDGNGSISDSLPSASPGSPHSGVQTSLEMFYSIDLSPVKCRSPLQTPSSGQFSSSPIQASAKKYSLGSITSPSPISSPTFSPIEFQIGETPLSEQRKFTVHSPDASSGTNSNGITNPCIRSPYIDGCSPIKNWSPMRLQMYSGGTQYRTSVIQIPFTLETQGEDEEDKENIPSTDVSSPAMDAAGIHLRQFSNEASTHGTHLVVTAMSVTQNQSSASEKELALLQDVEREKDNNTVDMVDPIEIADETTWIKEPVDNGSLPMTDFVSGIAFSIENSHMCMSPLAESSVIPCESSNIQMDSGYNTQNCGSNIMDTVGAESYCKESDAQTCEVESKSQAFNMKQDHTTQRCWMKTASPFQCSSP
種類予測
種類予測:
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Xenopus
89
Chicken
89
Rabbit
89
Zebrafish
78
Dog
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q6PGQ7 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y31 | Phosphorylation | Uniprot | |
| T38 | Phosphorylation | Uniprot | |
| S41 | Phosphorylation | Uniprot | |
| K46 | Ubiquitination | Uniprot | |
| T52 | Phosphorylation | Uniprot | |
| Y82 | Phosphorylation | Uniprot | |
| K95 | Acetylation | Uniprot | |
| K98 | Acetylation | Uniprot | |
| K106 | Acetylation | Uniprot | |
| K106 | Ubiquitination | Uniprot | |
| S112 | Phosphorylation | Uniprot | |
| K120 | Ubiquitination | Uniprot | |
| S135 | Phosphorylation | Uniprot | |
| S137 | Phosphorylation | Uniprot | |
| K142 | Ubiquitination | Uniprot | |
| S183 | Phosphorylation | Uniprot | |
| S188 | Phosphorylation | Uniprot | |
| S189 | Phosphorylation | Uniprot | |
| S190 | Phosphorylation | Uniprot | |
| S191 | Phosphorylation | Uniprot | |
| S239 | Phosphorylation | Uniprot | |
| S252 | Phosphorylation | P06493 (CDK1) | Uniprot |
| S270 | Phosphorylation | Uniprot | |
| S274 | Phosphorylation | P49841 (GSK3B) | Uniprot |
| S278 | Phosphorylation | P49841 (GSK3B) | Uniprot |
| T296 | Phosphorylation | Uniprot | |
| S299 | Phosphorylation | Uniprot | |
| S303 | Phosphorylation | Uniprot | |
| S318 | Phosphorylation | Uniprot | |
| S325 | Phosphorylation | P50750 (CDK9) | Uniprot |
| S331 | Phosphorylation | Uniprot | |
| S339 | Phosphorylation | Uniprot | |
| T432 | Phosphorylation | Uniprot | |
| T445 | Phosphorylation | Uniprot | |
| T446 | Phosphorylation | Uniprot | |
| S497 | Phosphorylation | P53350 (PLK1) | Uniprot |
| T501 | Phosphorylation | Q13535 (ATR) , P53350 (PLK1) | Uniprot |
| K531 | Ubiquitination | Uniprot | |
| K538 | Ubiquitination | Uniprot | |
| S552 | Phosphorylation | Uniprot | |
| S558 | Phosphorylation | Uniprot |
研究背景
機能:
Required for the activation of AURKA at the onset of mitosis.
PTMs:
Phosphorylated by AURKA.
サブユニット構造:
Interacts with AURKA.
タンパク質ファミリー:
Belongs to the BORA family.
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