Phospho-MAZ (Thr72) Antibody - #AF8282
| 製品: | Phospho-MAZ (Thr72) Antibody |
| カタログ: | AF8282 |
| タンパク質の説明: | Rabbit polyclonal antibody to Phospho-MAZ (Thr72) |
| アプリケーション: | WB |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig |
| 分子量: | 48 KD; 49kD(Calculated). |
| ユニプロット: | P56270 |
| RRID: | AB_2840344 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF8282, RRID:AB_2840344.
折りたたみ／展開
MAZ; MAZ_HUMAN; MAZI; MYC associated zinc finger protein; Myc-associated zinc finger protein; Pur-1; Pur1; Purine binding transcription factor; Purine-binding transcription factor; SAF 1; SAF 2; SAF-1; SAF-2; SAF-3; Serum amyloid A activating factor 1; Serum amyloid A activating factor 2; Transcription factor Zif87; ZF87; Zif87; Zinc finger protein 801; Zinc finger protein, 87 kilodaltons; ZNF801;
免疫原
Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and midfrontal cortex (at protein level).
- P56270 MAZ_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MFPVFPCTLLAPPFPVLGLDSRGVGGLMNSFPPPQGHAQNPLQVGAELQSRFFASQGCAQSPFQAAPAPPPTPQAPAAEPLQVDLLPVLAAAQESAAAAAAAAAAAAAVAAAPPAPAAASTVDTAALKQPPAPPPPPPPVSAPAAEAAPPASAATIAAAAATAVVAPTSTVAVAPVASALEKKTKSKGPYICALCAKEFKNGYNLRRHEAIHTGAKAGRVPSGAMKMPTMVPLSLLSVPQLSGAGGGGGEAGAGGGAAAVAAGGVVTTTASGKRIRKNHACEMCGKAFRDVYHLNRHKLSHSDEKPYQCPVCQQRFKRKDRMSYHVRSHDGAVHKPYNCSHCGKSFSRPDHLNSHVRQVHSTERPFKCEKCEAAFATKDRLRAHTVRHEEKVPCHVCGKMLSSAYISDHMKVHSQGPHHVCELCNKGTGEVCPMAAAAAAAAAAAAAAVAAPPTAVGSLSGAEGVPVSSQPLPSQPW
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P56270 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T72 | Phosphorylation | P27361 (MAPK3) | Uniprot |
| S186 | Phosphorylation | P17612 (PRKACA) | Uniprot |
| T213 | Phosphorylation | Uniprot | |
| K216 | Ubiquitination | Uniprot | |
| S222 | Phosphorylation | Uniprot | |
| S237 | Phosphorylation | Uniprot | |
| K273 | Acetylation | Uniprot | |
| K286 | Ubiquitination | Uniprot | |
| K298 | Ubiquitination | Uniprot | |
| S300 | Phosphorylation | Uniprot | |
| S302 | Phosphorylation | Uniprot | |
| K305 | Ubiquitination | Uniprot | |
| Y307 | Phosphorylation | Uniprot | |
| R321 | Methylation | Uniprot | |
| S323 | Phosphorylation | Uniprot | |
| Y324 | Phosphorylation | Uniprot | |
| R357 | Methylation | Uniprot | |
| S361 | Phosphorylation | Uniprot | |
| K378 | Acetylation | Uniprot | |
| K378 | Ubiquitination | Uniprot | |
| T385 | Phosphorylation | P31749 (AKT1) , P17612 (PRKACA) | Uniprot |
| S414 | Phosphorylation | Uniprot | |
| S460 | Phosphorylation | P68400 (CSNK2A1) | Uniprot |
| S469 | Phosphorylation | Uniprot | |
| S474 | Phosphorylation | Uniprot |
研究背景
May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. Regulates inflammation-induced expression of serum amyloid A proteins.
Nucleus.
Note: In brains of Alzheimer disease patients, present in a plaque-like structures.
Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and midfrontal cortex (at protein level).
Interacts with BPTF.
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