Phospho-HNRNPA0 (Ser84) Antibody - #AF8379
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF8379, RRID:AB_2840440.
折りたたみ／展開
Heterogeneous nuclear ribonucleoprotein A0; hnRNA binding protein; hnRNP A0; HNRNPA0; HNRPA0; ROA0_HUMAN;
免疫原
- Q13151 ROA0_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MENSQLCKLFIGGLNVQTSESGLRGHFEAFGTLTDCVVVVNPQTKRSRCFGFVTYSNVEEADAAMAASPHAVDGNTVELKRAVSREDSARPGAHAKVKKLFVGGLKGDVAEGDLIEHFSQFGTVEKAEIIADKQSGKKRGFGFVYFQNHDAADKAAVVKFHPIQGHRVEVKKAVPKEDIYSGGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGGGGGSSYGGSDYGNGFGGFGSYSQHQSSYGPMKSGGGGGGGGSSWGGRSNSGPYRGGYGGGGGYGGSSF
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q13151 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| S4 | Phosphorylation | Uniprot | |
| K8 | Ubiquitination | Uniprot | |
| S19 | Phosphorylation | Uniprot | |
| S21 | Phosphorylation | Uniprot | |
| K45 | Ubiquitination | Uniprot | |
| S47 | Phosphorylation | Uniprot | |
| T54 | Phosphorylation | Uniprot | |
| Y55 | Phosphorylation | Uniprot | |
| S68 | Phosphorylation | Uniprot | |
| T76 | Phosphorylation | Uniprot | |
| K80 | Ubiquitination | Uniprot | |
| S84 | Phosphorylation | P49137 (MAPKAPK2) | Uniprot |
| S88 | Phosphorylation | Uniprot | |
| K96 | Acetylation | Uniprot | |
| K96 | Sumoylation | Uniprot | |
| K96 | Ubiquitination | Uniprot | |
| K99 | Sumoylation | Uniprot | |
| K99 | Ubiquitination | Uniprot | |
| K106 | Sumoylation | Uniprot | |
| K106 | Ubiquitination | Uniprot | |
| S119 | Phosphorylation | Uniprot | |
| K126 | Sumoylation | Uniprot | |
| K126 | Ubiquitination | Uniprot | |
| K133 | Acetylation | Uniprot | |
| K133 | Sumoylation | Uniprot | |
| K133 | Ubiquitination | Uniprot | |
| S135 | Phosphorylation | Uniprot | |
| K138 | Sumoylation | Uniprot | |
| R139 | Methylation | Uniprot | |
| Y145 | Phosphorylation | Uniprot | |
| K154 | Sumoylation | Uniprot | |
| K154 | Ubiquitination | Uniprot | |
| K159 | Acetylation | Uniprot | |
| K159 | Sumoylation | Uniprot | |
| K159 | Ubiquitination | Uniprot | |
| K171 | Sumoylation | Uniprot | |
| K172 | Sumoylation | Uniprot | |
| K172 | Ubiquitination | Uniprot | |
| K176 | Sumoylation | Uniprot | |
| K176 | Ubiquitination | Uniprot | |
| Y180 | Phosphorylation | Uniprot | |
| S181 | Phosphorylation | Uniprot | |
| S188 | Phosphorylation | Uniprot | |
| R189 | Methylation | Uniprot | |
| R192 | Methylation | Uniprot | |
| R195 | Methylation | Uniprot | |
| R198 | Methylation | Uniprot | |
| R200 | Methylation | Uniprot | |
| R204 | Methylation | Uniprot | |
| K211 | Sumoylation | Uniprot | |
| Y217 | Phosphorylation | Uniprot | |
| Y231 | Phosphorylation | Uniprot | |
| Y234 | Phosphorylation | Uniprot | |
| Y265 | Phosphorylation | Uniprot | |
| K269 | Sumoylation | Uniprot | |
| S270 | Phosphorylation | Uniprot | |
| S279 | Phosphorylation | Uniprot | |
| S280 | Phosphorylation | Uniprot | |
| R284 | Methylation | Uniprot | |
| R291 | Methylation | Uniprot | |
| S303 | Phosphorylation | Uniprot |
研究背景
mRNA-binding component of ribonucleosomes. Specifically binds AU-rich element (ARE)-containing mRNAs. Involved in post-transcriptional regulation of cytokines mRNAs.
Phosphorylated at Ser-84 by MAPKAPK2 in response to LPS treatment, promoting stabilization of GADD45A mRNA.
Arg-291 is dimethylated, probably to asymmetric dimethylarginine.
Nucleus.
Note: Component of ribonucleosomes.
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