UBE2G1 Antibody - #DF10001
| 製品: | UBE2G1 Antibody |
| カタログ: | DF10001 |
| タンパク質の説明: | Rabbit polyclonal antibody to UBE2G1 |
| アプリケーション: | WB |
| 反応性: | Human, Mouse, Rat, Monkey |
| 予測: | Pig, Bovine, Horse, Sheep, Dog, Chicken, Xenopus |
| 分子量: | 20 kDa; 20kD(Calculated). |
| ユニプロット: | P62253 |
| RRID: | AB_2840581 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF10001, RRID:AB_2840581.
折りたたみ／展開
E217K; UB2G1_HUMAN; UBC 7; UBC7; UBC7 homolog yeast; UBE 2G; UBE2G; Ube2g1; Ubiquitin carrier protein G1; Ubiquitin conjugating enzyme E2 G1; Ubiquitin conjugating enzyme E2G 1 (homologous to C. elegans UBC7); Ubiquitin conjugating enzyme E2G 1 (UBC7 homolog C. elegans); Ubiquitin conjugating enzyme E2G 1 (UBC7 homolog yeast); Ubiquitin conjugating enzyme E2G 1; Ubiquitin protein ligase G1; Ubiquitin-conjugating enzyme E2 G1; Ubiquitin-protein ligase G1;
免疫原
- P62253 UB2G1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTELQSALLLRRQLAELNKNPVEGFSAGLIDDNDLYRWEVLIIGPPDTLYEGGVFKAHLTFPKDYPLRPPKMKFITEIWHPNVDKNGDVCISILHEPGEDKYGYEKPEERWLPIHTVETIMISVISMLADPNGDSPANVDAAKEWREDRNGEFKRKVARCVRKSQETAFE
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P62253 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| T2 | Acetylation | Uniprot | |
| T2 | Phosphorylation | Uniprot | |
| S6 | Phosphorylation | Uniprot | |
| K19 | Ubiquitination | Uniprot | |
| K63 | Ubiquitination | Uniprot | |
| Y65 | Phosphorylation | Uniprot | |
| K73 | Ubiquitination | Uniprot | |
| T76 | Phosphorylation | Uniprot | |
| K101 | Ubiquitination | Uniprot | |
| Y102 | Phosphorylation | Uniprot | |
| Y104 | Phosphorylation | Uniprot | |
| K106 | Ubiquitination | Uniprot | |
| K163 | Ubiquitination | Uniprot |
研究背景
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. May be involved in degradation of muscle-specific proteins. Mediates polyubiquitination of CYP3A4.
Autoubiquitinated in vitro.
Widely expressed, mainly in skeletal muscle.
Belongs to the ubiquitin-conjugating enzyme family.
研究領域
· Genetic Information Processing > Folding, sorting and degradation > Ubiquitin mediated proteolysis. (View pathway)
· Genetic Information Processing > Folding, sorting and degradation > Protein processing in endoplasmic reticulum. (View pathway)
· Human Diseases > Neurodegenerative diseases > Parkinson's disease.
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