POLM Antibody - #DF10080
| 製品: | POLM Antibody |
| カタログ: | DF10080 |
| タンパク質の説明: | Rabbit polyclonal antibody to POLM |
| アプリケーション: | WB |
| 反応性: | Human |
| 予測: | Pig, Zebrafish, Horse, Sheep, Rabbit |
| 分子量: | 55 kDa; 55kD(Calculated). |
| ユニプロット: | Q9NP87 |
| RRID: | AB_2840660 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF10080, RRID:AB_2840660.
折りたたみ／展開
DNA-directed DNA polymerase mu; DNA-directed DNA/RNA polymerase mu; DPOLM_HUMAN; FLJ35482; Pol iota; Pol Mu; Polm; POLM protein; Polymerase (DNA directed) mu; Polymerase DNA directed mu; Tdt N; Tdt-N; TdtN; Terminal transferase;
免疫原
- Q9NP87 DPOLM_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLPKRRRARVGSPSGDAASSTPPSTRFPGVAIYLVEPRMGRSRRAFLTGLARSKGFRVLDACSSEATHVVMEETSAEEAVSWQERRMAAAPPGCTPPALLDISWLTESLGAGQPVPVECRHRLEVAGPRKGPLSPAWMPAYACQRPTPLTHHNTGLSEALEILAEAAGFEGSEGRLLTFCRAASVLKALPSPVTTLSQLQGLPHFGEHSSRVVQELLEHGVCEEVERVRRSERYQTMKLFTQIFGVGVKTADRWYREGLRTLDDLREQPQKLTQQQKAGLQHHQDLSTPVLRSDVDALQQVVEEAVGQALPGATVTLTGGFRRGKLQGHDVDFLITHPKEGQEAGLLPRVMCRLQDQGLILYHQHQHSCCESPTRLAQQSHMDAFERSFCIFRLPQPPGAAVGGSTRPCPSWKAVRVDLVVAPVSQFPFALLGWTGSKLFQRELRRFSRKEKGLWLNSHGLFDPEQKTFFQAASEEDIFRHLGLEYLPPEQRNA
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9NP87 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S12 | Phosphorylation | Uniprot | |
| S14 | Phosphorylation | Uniprot | |
| S19 | Phosphorylation | Uniprot | |
| T21 | Phosphorylation | Uniprot | |
| T95 | Phosphorylation | Uniprot | |
| K187 | Ubiquitination | Uniprot | |
| K238 | Ubiquitination | Uniprot | |
| K249 | Ubiquitination | Uniprot | |
| K271 | Ubiquitination | Uniprot | |
| K277 | Ubiquitination | Uniprot | |
| K325 | Ubiquitination | Uniprot | |
| K339 | Ubiquitination | Uniprot | |
| S372 | Phosphorylation | P24941 (CDK2) | Uniprot |
| K452 | Ubiquitination | Uniprot | |
| K467 | Ubiquitination | Uniprot |
研究背景
Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination.
Nucleus.
Expressed in a number of tissues. Abundant in thymus.
Belongs to the DNA polymerase type-X family.
研究領域
· Genetic Information Processing > Replication and repair > Non-homologous end-joining.
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.