製品: CSNK1G3 Antibody
カタログ: DF10135
タンパク質の説明: Rabbit polyclonal antibody to CSNK1G3
アプリケーション: WB IHC
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
分子量: 51 kDa; 51kD(Calculated).
ユニプロット: Q9Y6M4
RRID: AB_2840715

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 100ul $280 在庫あり
 200ul $350 在庫あり

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Bovine(89%), Horse(100%), Sheep(90%), Rabbit(100%), Dog(100%), Xenopus(91%)
クローナリティ:
Polyclonal
特異性:
CSNK1G3 Antibody detects endogenous levels of total CSNK1G3.
RRID:
AB_2840715
引用形式: Affinity Biosciences Cat# DF10135, RRID:AB_2840715.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

casein kinase 1 gamma 3; casein kinase I gamma 3; Casein kinase I isoform gamma 3; Casein kinase I isoform gamma-3; CKI-gamma 3; Csnk1g3; CSNK1G3L; KC1G3_HUMAN;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MENKKKDKDKSDDRMARPSGRSGHNTRGTGSSSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKMQQSKNQSADHRAAWDSQQANPHHLRAHLAADRHGGSVQVVSSTNGELNTDDPTAGRSNAPITAPTEVEVMDETKCCCFFKRRKRKTIQRHK

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Dog
100
Rabbit
100
Xenopus
91
Sheep
90
Bovine
89
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9Y6M4 基板として

Site PTM Type Enzyme
M1 Acetylation
S11 Phosphorylation
T29 Phosphorylation
S31 Phosphorylation
S32 Phosphorylation
S34 Phosphorylation
K48 Ubiquitination
K61 Ubiquitination
Y64 Phosphorylation
T65 Phosphorylation
Y68 Phosphorylation
Y87 Phosphorylation
Y90 Phosphorylation
K91 Methylation
Y160 Phosphorylation
K164 Ubiquitination
K176 Ubiquitination
Y192 Phosphorylation
K253 Ubiquitination
T256 Phosphorylation
K263 Ubiquitination
K306 Ubiquitination
S344 Phosphorylation
S345 Phosphorylation
S392 Phosphorylation
S397 Phosphorylation
S398 Phosphorylation
S413 Phosphorylation
T421 Phosphorylation
K430 Ubiquitination
K436 Ubiquitination

研究背景

機能:

Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate (By similarity).

PTMs:

Autophosphorylated.

細胞の位置付け:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Monomer.

タンパク質ファミリー:

Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

研究領域

· Environmental Information Processing > Signal transduction > Hedgehog signaling pathway.   (View pathway)

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