製品: CD1B Antibody
カタログ: DF10150
タンパク質の説明: Rabbit polyclonal antibody to CD1B
アプリケーション: WB
反応性: Human, Rat
予測: Dog
分子量: 37 kDa; 37kD(Calculated).
ユニプロット: P29016
RRID: AB_2840729

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Rat
予測:
Dog(88%)
クローナリティ:
Polyclonal
特異性:
CD1B Antibody detects endogenous levels of total CD1B.
RRID:
AB_2840729
引用形式: Affinity Biosciences Cat# DF10150, RRID:AB_2840729.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

A1 domain; CD1; CD1A; CD1b; CD1b antigen; CD1B antigen b polypeptide; CD1b molecule; CD1B_HUMAN; Cortical thymocyte antigen CD1A; Cortical thymocyte antigen CD1B; Differentiation antigen CD1 alpha 3; hTa1 thymocyte antigen; Ly38; Ly38; T cell surface glycoprotein CD1a; MGC125990; MGC125991; R1; T-cell surface glycoprotein CD1b; T6/Leu6; Thymocite antigen CD1B;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
P29016 CD1B_HUMAN:

Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.

タンパク質配列:
MLLLPFQLLAVLFPGGNSEHAFQGPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIAGCELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQGIMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRNPTSIGSIVLAIIVPSLLLLLCLALWYMRRRSYQNIP

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Dog
88
Pig
0
Horse
0
Bovine
0
Sheep
0
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P29016 基板として

Site PTM Type Enzyme
N38 N-Glycosylation
N75 N-Glycosylation
Y110 Phosphorylation
K145 Ubiquitination
K196 Ubiquitination
K204 Ubiquitination

研究背景

機能:

Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.

細胞の位置付け:

Cell membrane>Single-pass type I membrane protein. Endosome membrane>Single-pass type I membrane protein. Lysosome membrane>Single-pass type I membrane protein.
Note: Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.

サブユニット構造:

Heterodimer with B2M (beta-2-microglobulin). Interacts with saposin C.

研究領域

· Cellular Processes > Cellular community - eukaryotes > Tight junction.   (View pathway)

· Organismal Systems > Immune system > Hematopoietic cell lineage.   (View pathway)

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