LILRB5 Antibody - #DF10152
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF10152, RRID:AB_2840731.
折りたたみ／展開
CD85 antigen-like family member C; CD85c; Leukocyte immunoglobulin-like receptor 8; Leukocyte immunoglobulin-like receptor subfamily B member 5; LILRB5; LIR-8; LIR8; LIRB5_HUMAN;
免疫原
- O75023 LIRB5_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGFYAEPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPGPEDQPLTPTGLDPQSGLGRHLGVVTGVSVAFVLLLFLLLFLLLRHRHQSKHRTSAHFYRPAGAAGPEPKDQGLQKRASPVADIQEEILNAAVKDTQPKDGVEMDARAAASEAPQDVTYAQLHSLTLRREATEPPPSQEREPPAEPSIYAPLAIH
PTMs - O75023 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S225 | Phosphorylation | Uniprot | |
| N279 | N-Glycosylation | Uniprot | |
| T489 | Phosphorylation | Uniprot | |
| S490 | Phosphorylation | Uniprot | |
| S514 | Phosphorylation | Uniprot | |
| T553 | Phosphorylation | Uniprot | |
| Y554 | Phosphorylation | Uniprot | |
| S559 | Phosphorylation | Uniprot | |
| Y584 | Phosphorylation | Uniprot |
研究背景
May act as receptor for class I MHC antigens.
Membrane>Single-pass type I membrane protein.
Detected in a natural killer (NK) cells.
Contains 2 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.
研究領域
· Organismal Systems > Development > Osteoclast differentiation. (View pathway)
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