PSD4 Antibody - #DF10161
| 製品: | PSD4 Antibody |
| カタログ: | DF10161 |
| タンパク質の説明: | Rabbit polyclonal antibody to PSD4 |
| アプリケーション: | WB |
| 反応性: | Human |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 116kDa; 116kD(Calculated). |
| ユニプロット: | Q8NDX1 |
| RRID: | AB_2840740 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF10161, RRID:AB_2840740.
折りたたみ／展開
EFA6B; Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B; FLJ36237; FLJ37279; PH and SEC7 domain-containing protein 4; Pleckstrin homology and SEC7 domain-containing protein 4; Ppleckstrin and Sec7 domain containing 4; PSD4; PSD4_HUMAN; SEC7 homolog antibody | telomeric of interleukin-1 cluster protein; Telomeric of interleukin-1 cluster protein; TIC;
免疫原
Widely expressed. Highest levels of expression are found in placenta, pancreas, spleen, thymus and peripheral blood.
- Q8NDX1 PSD4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MMGDYRLPDHPQPMEILNLYLGDSLEPHPGECPRETCSHEDPPEPFEEQTWATDPPEPTRQNVPPWGSGVELTHLGSWVHQDGLEPCQEQTRATDPPESTRQDAPPWGSGVELTHLGSPSAQREHRQNTASPGSPVNSHLPGSPKQNRSTSTQVVFWAGILQAQMCVLDLEEELEKTEGLKAGLKCCLPTPPVDLPGDTGLHSSPPENEDSGEDSSEPEGEGQAWLREGTPDSSPQWGAEEESMFFSNPLFLASPCSENSASGECFSWGASDSHAGVRTGPESPATLEPPLPEDTVLWELESEPDLGDGAAISGHCTPPFPVPIYKPHSICWASVAAAEGAPAAPPGHGESEGDRLGPAPSAAPCVDEALTWESGCVGSDLGPAAHPVQPWASLSPEGWQRGGPFWPQVTLNSQDRDEREGGHPQESLPCTLAPCPWRSPASSPEPSSPESESRGPGPRPSPASSQEGSPQLQHHSSGILPKWTLDASQSSLLETDGEQPSSLKKKEAGEAPKPGEEVKSEGTARPAETGDVQPDIHLTSAEHENLRTPMNSSWLPGSPMPQAQSPEEGQRPPAGDKLANGVRNNKVAWNLASRLYRLEGFRKSEVAAYLQKNNDFSRAVAEEYLSFFQFGGQSLDRALRSFLQALVLSGETQERERILYQFSRRFHHCNPGIFPSVDSVHTLTCAIMLLNTDLHGQNIGKSMSCQEFITNLNGLRDGGNFPKELLKALYWSIRSEKLEWAVDEEDTARPEKAQPSLPAGKMSKPFLQLAQDPTVPTYKQGILARKMHQDADGKKTPWGKRGWKMFHTLLRGMVLYFLKQGEDHCLEGESLVGQMVDEPVGVHHSLATPATHYTKKPHVFQLRTADWRLYLFQAPTAKEMSSWIARINLAAATHSAPPFPAAVGSQRRFVRPILPVGPAQSSLEEQHRSHENCLDAAADDLLDLQRNLPERRGRGRELEEHRLRKEYLEYEKTRYETYVQLLVARLHCPSDALDLWEEQLGREAGGTREPKLSLKKSHSSPSLHQDEAPTTAKVKRNISERRTYRKIIPKRNRNQL
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q8NDX1 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T50 | Phosphorylation | Uniprot | |
| S68 | Phosphorylation | Uniprot | |
| S77 | Phosphorylation | Uniprot | |
| S109 | Phosphorylation | Uniprot | |
| T114 | Phosphorylation | Uniprot | |
| S118 | Phosphorylation | Uniprot | |
| S131 | Phosphorylation | Uniprot | |
| S134 | Phosphorylation | Uniprot | |
| S138 | Phosphorylation | Uniprot | |
| S143 | Phosphorylation | Uniprot | |
| K181 | Ubiquitination | Uniprot | |
| T230 | Phosphorylation | Uniprot | |
| S233 | Phosphorylation | Uniprot | |
| T317 | Phosphorylation | Uniprot | |
| S395 | Phosphorylation | Uniprot | |
| T410 | Phosphorylation | Uniprot | |
| S413 | Phosphorylation | Uniprot | |
| S448 | Phosphorylation | Uniprot | |
| S461 | Phosphorylation | Uniprot | |
| S464 | Phosphorylation | Uniprot | |
| S465 | Phosphorylation | Uniprot | |
| S469 | Phosphorylation | Uniprot | |
| S488 | Phosphorylation | Uniprot | |
| S490 | Phosphorylation | Uniprot | |
| S491 | Phosphorylation | Uniprot | |
| T495 | Phosphorylation | Uniprot | |
| S501 | Phosphorylation | Uniprot | |
| S502 | Phosphorylation | Uniprot | |
| T548 | Phosphorylation | Uniprot | |
| S558 | Phosphorylation | Uniprot | |
| S565 | Phosphorylation | Uniprot | |
| K586 | Ubiquitination | Uniprot | |
| K603 | Ubiquitination | Uniprot | |
| K723 | Ubiquitination | Uniprot | |
| K752 | Ubiquitination | Uniprot | |
| K761 | Ubiquitination | Uniprot | |
| S763 | Phosphorylation | Uniprot | |
| K764 | Ubiquitination | Uniprot | |
| K779 | Ubiquitination | Uniprot | |
| K786 | Ubiquitination | Uniprot | |
| T808 | Phosphorylation | Uniprot | |
| Y816 | Phosphorylation | Uniprot | |
| S905 | Phosphorylation | Uniprot | |
| Y975 | Phosphorylation | Uniprot | |
| S1013 | Phosphorylation | Uniprot | |
| K1016 | Ubiquitination | Uniprot | |
| S1017 | Phosphorylation | Uniprot | |
| S1019 | Phosphorylation | Uniprot | |
| S1020 | Phosphorylation | Uniprot | |
| S1022 | Phosphorylation | Uniprot | |
| T1031 | Phosphorylation | Uniprot | |
| S1039 | Phosphorylation | Uniprot | |
| T1043 | Phosphorylation | Uniprot | |
| K1046 | Ubiquitination | Uniprot |
研究背景
Guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Through ARL14 activation, controls the movement of MHC class II-containing vesicles along the actin cytoskeleton in dendritic cells. Involved in membrane recycling. Interacts with several phosphatidylinositol phosphate species, including phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 4,5-bisphosphate.
Cell membrane. Cell projection>Ruffle membrane.
Note: In interphase associated with the plasma membrane, in particular with membrane ruffling regions (PubMed:23603394). Accumulates in dynamic actin-rich membrane ruffles and microvilli-like structures (PubMed:12082148). Recruited to membranes via phosphatidylinositol phosphate-binding (Probable).
Widely expressed. Highest levels of expression are found in placenta, pancreas, spleen, thymus and peripheral blood.
研究領域
· Cellular Processes > Transport and catabolism > Endocytosis. (View pathway)
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