製品: CDC37L1 Antibody
カタログ: DF10175
タンパク質の説明: Rabbit polyclonal antibody to CDC37L1
アプリケーション: WB IHC IF/ICC
反応性: Human, Rat
予測: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
分子量: 39 kDa; 39kD(Calculated).
ユニプロット: Q7L3B6
RRID: AB_2840754

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製品説明

ソース:
Rabbit
アプリケーション:
IHC 1:50-1:200, WB 1:1000-3000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Rat
予測:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(92%), Xenopus(92%)
クローナリティ:
Polyclonal
特異性:
CDC37L1 Antibody detects endogenous levels of total CDC37L1.
RRID:
AB_2840754
引用形式: Affinity Biosciences Cat# DF10175, RRID:AB_2840754.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

CD37L_HUMAN; CDC37 cell division cycle 37 homolog like 1; CDC37-like 1; CDC37B; Cdc37l; Cdc37l1; Cell division cycle 37 homolog (S. cerevisiae) like 1; Cell division cycle 37, S. cerevisiae, homolog-like 1; FLJ20639; HARC; Hsp90 associating relative of Cdc37; Hsp90 co-chaperone Cdc37-like 1; Hsp90-associating relative of Cdc37; RP11-6J24.5;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q7L3B6 CD37L_HUMAN:

Expressed in brain, heart, kidney, liver, placenta and skeletal muscle.

タンパク質配列:
MEQPWPPPGPWSLPRAEGEAEEESDFDVFPSSPRCPQLPGGGAQMYSHGIELACQKQKEFVKSSVACKWNLAEAQQKLGSLALHNSESLDQEHAKAQTAVSELRQREEEWRQKEEALVQREKMCLWSTDAISKDVFNKSFINQDKRKDTEDEDKSESFMQKYEQKIRHFGMLSRWDDSQRFLSDHPYLVCEETAKYLILWCFHLEAEKKGALMEQIAHQAVVMQFIMEMAKNCNVDPRGCFRLFFQKAKAEEEGYFEAFKNELEAFKSRVRLYSQSQSFQPMTVQNHVPHSGVGSIGLLESLPQNPDYLQYSISTALCSLNSVVHKEDDEPKMMDTV

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Rabbit
100
Xenopus
92
Chicken
92
Zebrafish
58
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q7L3B6 基板として

Site PTM Type Enzyme
S31 Phosphorylation
S32 Phosphorylation
K62 Methylation
K62 Ubiquitination
K77 Ubiquitination
S88 Phosphorylation
K95 Ubiquitination
T98 Phosphorylation
S101 Phosphorylation
K113 Ubiquitination
K138 Ubiquitination
K260 Ubiquitination

研究背景

機能:

Co-chaperone that binds to numerous proteins and promotes their interaction with Hsp70 and Hsp90.

細胞の位置付け:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in brain, heart, kidney, liver, placenta and skeletal muscle.

サブユニット構造:

Self-associates. Forms complexes with Hsp70 and Hsp90. Interacts with CDC37, FKBP4, PPID and STIP1.

タンパク質ファミリー:

Belongs to the CDC37 family.

Restrictive clause

 

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For Research Use Only.
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