製品: RLN3 Antibody
カタログ: DF10177
タンパク質の説明: Rabbit polyclonal antibody to RLN3
アプリケーション: WB IF/ICC
反応性: Human
予測: Pig, Bovine, Sheep, Rabbit
分子量: 15 kDa; 15kD(Calculated).
ユニプロット: Q8WXF3
RRID: AB_2840756

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製品説明

ソース:
Rabbit
アプリケーション:
IF/ICC 1:100-1:500, WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
予測:
Pig(86%), Bovine(100%), Sheep(83%), Rabbit(86%)
クローナリティ:
Polyclonal
特異性:
RLN3 Antibody detects endogenous levels of total RLN3.
RRID:
AB_2840756
引用形式: Affinity Biosciences Cat# DF10177, RRID:AB_2840756.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

H3; INSL 7; INSL7; Insulin like 7; Insulin like peptide 7; Insulin like peptide INSL7; Insulin like7; Insulinlike 7; Prorelaxin H3; Prorelaxin M3; REL 3; REL3; Relaxin 3; Relaxin 3 (H3); Relaxin 3 A chain; Relaxin 3 B chain; Relaxin 3 precursor; Relaxin3; RLN 3; RLN3; RXN 3; RXN3; ZINS 4; ZINS4;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MARYMLLLLLAVWVLTGELWPGAEARAAPYGVRLCGREFIRAVIFTCGGSRWRRSDILAHEAMGDTFPDADADEDSLAGELDEAMGSSEWLALTKSPQAFYRGRPSWQGTPGVLRGSRDVLAGLSSSCCKWGCSKSEISSLC

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Bovine
100
Pig
86
Rabbit
86
Sheep
83
Horse
0
Dog
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q8WXF3 基板として

Site PTM Type Enzyme
Y30 Phosphorylation

研究背景

機能:

May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 (GPCR135) and relaxin-3 receptor-2 (GPCR142).

細胞の位置付け:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Heterodimer of a B chain and an A chain linked by two disulfide bonds.

タンパク質ファミリー:

Belongs to the insulin family.

研究領域

· Organismal Systems > Endocrine system > Relaxin signaling pathway.

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