STA13 Antibody - #AF0732
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(6)
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF0732, RRID:AB_2834356.
折りたたみ／展開
46H23.2; ARHGAP37; Deleted in liver cancer 2 protein; Deleted in liver cancer protein 2; DLC-2; DLC2; GT650; Rho GTPase activating protein on chromosome 13q12; Rho GTPase-activating protein; STA13; STA13_HUMAN; StAR related lipid transfer (START) domain containing 13; StAR-related lipid transfer protein 13; StARD13; START domain-containing protein 13;
免疫原
Ubiquitously expressed. Underexpressed in hepatocellular carcinoma cells and some breast cancer cell lines.
- Q9Y3M8 STA13_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MFSQVPRTPASGCYYLNSMTPEGQEMYLRFDQTTRRSPYRMSRILARHQLVTKIQQEIEAKEACDWLRAAGFPQYAQLYEDSQFPINIVAVKNDHDFLEKDLVEPLCRRLNTLNKCASMKLDVNFQRKKGDDSDEEDLCISNKWTFQRTSRRWSRVDDLYTLLPRGDRNGSPGGTGMRNTTSSESVLTDLSEPEVCSIHSESSGGSDSRSQPGQCCTDNPVMLDAPLVSSSLPQPPRDVLNHPFHPKNEKPTRARAKSFLKRMETLRGKGAHGRHKGSGRTGGLVISGPMLQQEPESFKAMQCIQIPNGDLQNSPPPACRKGLPCSGKSSGESSPSEHSSSGVSTPCLKERKCHEANKRGGMYLEDLDVLAGTALPDAGDQSRMHEFHSQENLVVHIPKDHKPGTFPKALSIESLSPTDSSNGVNWRTGSISLGREQVPGAREPRLMASCHRASRVSIYDNVPGSHLYASTGDLLDLEKDDLFPHLDDILQHVNGLQEVVDDWSKDVLPELQTHDTLVGEPGLSTFPSPNQITLDFEGNSVSEGRTTPSDVERDVTSLNESEPPGVRDRRDSGVGASLTRPNRRLRWNSFQLSHQPRPAPASPHISSQTASQLSLLQRFSLLRLTAIMEKHSMSNKHGWTWSVPKFMKRMKVPDYKDKAVFGVPLIVHVQRTGQPLPQSIQQALRYLRSNCLDQVGLFRKSGVKSRIHALRQMNENFPENVNYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETFLHIYQYVSKEQRLQAVQAAILLLADENREVLQTLLCFLNDVVNLVEENQMTPMNLAVCLAPSLFHLNLLKKESSPRVIQKKYATGKPDQKDLNENLAAAQGLAHMIMECDRLFEVPHELVAQSRNSYVEAEIHVPTLEELGTQLEESGATFHTYLNHLIQGLQKEAKEKFKGWVTCSSTDNTDLAFKKVGDGNPLKLWKASVEVEAPPSVVLNRVLRERHLWDEDFVQWKVVETLDRQTEIYQYVLNSMAPHPSRDFVVLRTWKTDLPKGMCTLVSLSVEHEEAQLLGGVRAVVMDSQYLIEPCGSGKSRLTHICRIDLKGHSPEWYSKGFGHLCAAEVARIRNSFQPLIAEGPETKI
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9Y3M8 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| S3 | Phosphorylation | Uniprot | |
| S37 | Phosphorylation | Uniprot | |
| Y39 | Phosphorylation | Uniprot | |
| S42 | Phosphorylation | Uniprot | |
| K100 | Ubiquitination | Uniprot | |
| S118 | Phosphorylation | Uniprot | |
| S133 | Phosphorylation | Uniprot | |
| S141 | Phosphorylation | Uniprot | |
| S154 | Phosphorylation | Uniprot | |
| Y160 | Phosphorylation | Uniprot | |
| T161 | Phosphorylation | Uniprot | |
| S171 | Phosphorylation | Uniprot | |
| K247 | Ubiquitination | Uniprot | |
| R267 | Methylation | Uniprot | |
| S314 | Phosphorylation | Uniprot | |
| S334 | Phosphorylation | Uniprot | |
| T345 | Phosphorylation | Uniprot | |
| S389 | Phosphorylation | Uniprot | |
| S411 | Phosphorylation | Uniprot | |
| S414 | Phosphorylation | Uniprot | |
| S416 | Phosphorylation | Uniprot | |
| S430 | Phosphorylation | Uniprot | |
| S454 | Phosphorylation | Uniprot | |
| S457 | Phosphorylation | Uniprot | |
| Y459 | Phosphorylation | Uniprot | |
| Y468 | Phosphorylation | Uniprot | |
| S470 | Phosphorylation | Uniprot | |
| T547 | Phosphorylation | Uniprot | |
| S572 | Phosphorylation | Uniprot | |
| S577 | Phosphorylation | Uniprot | |
| S589 | Phosphorylation | Uniprot | |
| S828 | Phosphorylation | Uniprot | |
| S829 | Phosphorylation | Uniprot | |
| T930 | Phosphorylation | Uniprot | |
| K942 | Ubiquitination | Uniprot |
研究背景
GTPase-activating protein for RhoA, and perhaps for Cdc42. May be involved in regulation of cytoskeletal reorganization, cell proliferation and cell motility. Acts a tumor suppressor in hepatocellular carcinoma cells.
Cytoplasm. Membrane>Peripheral membrane protein>Cytoplasmic side. Mitochondrion membrane>Peripheral membrane protein>Cytoplasmic side. Lipid droplet.
Ubiquitously expressed. Underexpressed in hepatocellular carcinoma cells and some breast cancer cell lines.
Homodimer. Interacts with TAX1BP1.
参考文献
Application: WB Species: Mouse Sample: mHSCs
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