GH1 Antibody - #DF10188
製品: | GH1 Antibody |
カタログ: | DF10188 |
タンパク質の説明: | Rabbit polyclonal antibody to GH1 |
アプリケーション: | WB |
反応性: | Human |
分子量: | 25 kDa; 25kD(Calculated). |
ユニプロット: | P01241 |
RRID: | AB_2840767 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF10188, RRID:AB_2840767.
折りたたみ/展開
gH; GH-N; GH1; GHB5; GHN; Growth hormone 1; Growth hormone; Growth hormone B5; Growth hormone, normal; Growth hormone, pituitary; HG1; hGH-N; IGHD1B; Pituitary growth hormone; RNGHGP; SOMA_HUMAN; Somatotropin;
免疫原
- P01241 SOMA_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MATGSRTSLLLAFGLLCLPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF
PTMs - P01241 基板として
Site | PTM Type | Enzyme | Source |
---|---|---|---|
Y68 | Phosphorylation | Uniprot | |
S77 | Phosphorylation | Uniprot | |
T93 | Phosphorylation | Uniprot | |
S97 | Phosphorylation | Uniprot | |
S132 | Phosphorylation | Uniprot | |
S176 | Phosphorylation | Uniprot |
研究背景
Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
Secreted.
Monomer, dimer, trimer, tetramer and pentamer, disulfide-linked or non-covalently associated, in homopolymeric and heteropolymeric combinations. Can also form a complex either with GHBP or with the alpha2-macroglobulin complex.
Belongs to the somatotropin/prolactin family.
研究領域
· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction. (View pathway)
· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.
· Environmental Information Processing > Signal transduction > PI3K-Akt signaling pathway. (View pathway)
· Environmental Information Processing > Signal transduction > Jak-STAT signaling pathway. (View pathway)
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