製品: ENOSF1 Antibody
カタログ: DF10190
タンパク質の説明: Rabbit polyclonal antibody to ENOSF1
アプリケーション: WB
反応性: Human
予測: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
分子量: 50 kDa; 50kD(Calculated).
ユニプロット: Q7L5Y1
RRID: AB_2840769

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
予測:
Pig(92%), Bovine(92%), Horse(92%), Sheep(92%), Rabbit(83%), Dog(92%), Xenopus(100%)
クローナリティ:
Polyclonal
特異性:
ENOSF1 Antibody detects endogenous levels of total ENOSF1.
RRID:
AB_2840769
引用形式: Affinity Biosciences Cat# DF10190, RRID:AB_2840769.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Antisense RNA to thymidylate synthase; ENOF1_HUMAN; Enolase superfamily member 1; ENOSF 1; enosf1; HSRTSBETA; Mitochondrial enolase superfamily member 1; RTS alpha; RTS; RTS beta; RTS beta protein; TYMSAS;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MVRGRISRLSVRDVRFPTSLGGHGADAMHTDPDYSAAYVVIETDAEDGIKGCGITFTLGKGTEVVVCAVNALAHHVLNKDLKDIVGDFRGFYRQLTSDGQLRWIGPEKGVVHLATAAVLNAVWDLWAKQEGKPVWKLLVDMDPRMLVSCIDFRYITDVLTEEDALEILQKGQIGKKEREKQMLAQGYPAYTTSCAWLGYSDDTLKQLCAQALKDGWTRFKVKVGADLQDDMRRCQIIRDMIGPEKTLMMDANQRWDVPEAVEWMSKLAKFKPLWIEEPTSPDDILGHATISKALVPLGIGIATGEQCHNRVIFKQLLQAKALQFLQIDSCRLGSVNENLSVLLMAKKFEIPVCPHAGGVGLCELVQHLIIFDYISVSASLENRVCEYVDHLHEHFKYPVMIQRASYMPPKDPGYSTEMKEESVKKHQYPDGEVWKKLLPAQEN

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Xenopus
100
Pig
92
Horse
92
Bovine
92
Sheep
92
Dog
92
Rabbit
83
Zebrafish
75
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q7L5Y1 基板として

Site PTM Type Enzyme
K82 Ubiquitination
K132 Ubiquitination
S148 Phosphorylation
K170 Ubiquitination
K222 Ubiquitination
T246 Phosphorylation
K266 Ubiquitination
K271 Ubiquitination
K314 Ubiquitination
Y397 Phosphorylation
K425 Ubiquitination
K435 Ubiquitination
K436 Ubiquitination

研究背景

機能:

Plays a role in the catabolism of L-fucose, a sugar that is part of the carbohydrates that are attached to cellular glycoproteins. Catalyzes the dehydration of L-fuconate to 2-keto-3-deoxy-L-fuconate by the abstraction of the 2-proton to generate an enediolate intermediate that is stabilized by the magnesium ion.

PTMs:

Could be sumoylated.

細胞の位置付け:

Mitochondrion.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
タンパク質ファミリー:

Belongs to the mandelate racemase/muconate lactonizing enzyme family. ENOSF1 subfamily.

研究領域

· Metabolism > Carbohydrate metabolism > Fructose and mannose metabolism.

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