TNFRSF17 Antibody - #DF10193
| 製品: | TNFRSF17 Antibody |
| カタログ: | DF10193 |
| タンパク質の説明: | Rabbit polyclonal antibody to TNFRSF17 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Rat |
| 予測: | Horse, Dog |
| 分子量: | 20 kDa; 20kD(Calculated). |
| ユニプロット: | Q02223 |
| RRID: | AB_2840772 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF10193, RRID:AB_2840772.
折りたたみ／展開
B cell maturation antigen; B cell maturation factor; B cell maturation protein; B-cell maturation protein; BCM; BCMA; CD269; CD269 antigen; TNFRSF17; TNR17_HUMAN; Tumor necrosis factor receptor superfamily member 17;
免疫原
- Q02223 TNR17_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLQMAGQCSQNEYFDSLLHACIPCQLRCSSNTPPLTCQRYCNASVTNSVKGTNAILWTCLGLSLIISLAVFVLMFLLRKINSEPLKDEFKNTGSGLLGMANIDLEKSRTGDEIILPRGLEYTVEECTCEDCIKSKPKVDSDHCFPLPAMEEGATILVTTKTNDYCKSLPAALSATEIEKSISAR
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q02223 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K86 | Acetylation | Uniprot | |
| K86 | Ubiquitination | Uniprot | |
| K106 | Acetylation | Uniprot | |
| K106 | Ubiquitination | Uniprot | |
| Y121 | Phosphorylation | Uniprot | |
| K133 | Ubiquitination | Uniprot | |
| K135 | Ubiquitination | Uniprot | |
| K137 | Ubiquitination | Uniprot | |
| K160 | Ubiquitination | Uniprot | |
| K166 | Ubiquitination | Uniprot | |
| S173 | Phosphorylation | Uniprot | |
| K179 | Ubiquitination | Uniprot |
研究背景
Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
Cell membrane>Single-pass type III membrane protein. Endomembrane system>Single-pass type III membrane protein.
Note: Perinuclear Golgi-like structures.
Expressed in mature B-cells, but not in T-cells or monocytes.
Associates with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6.
研究領域
· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction. (View pathway)
· Organismal Systems > Immune system > Intestinal immune network for IgA production. (View pathway)
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