HTR3C Antibody - #DF10196
| 製品: | HTR3C Antibody |
| カタログ: | DF10196 |
| タンパク質の説明: | Rabbit polyclonal antibody to HTR3C |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Rat |
| 分子量: | 50 kDa; 50kD(Calculated). |
| ユニプロット: | Q8WXA8 |
| RRID: | AB_2840775 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF10196, RRID:AB_2840775.
折りたたみ／展開
5 HT3 C; 5 HT3C; 5 hydroxytryptamine (serotonin) receptor 3, family member C; 5 hydroxytryptamine (serotonin) receptor 3C ionotropic; 5 hydroxytryptamine receptor 3 subunit C; 5 hydroxytryptamine receptor 3C; Serotonin receptor 3C;
免疫原
Expressed in many tissues including adult brain, colon, intestine, lung, muscle and stomach as well as fetal colon and kidney.
- Q8WXA8 5HT3C_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEGGWPARQSALLCLTVSLLLQGRGDAFTINCSGFDQHGVDPAVFQAVFDRKAFRPFTNYSIPTRVNISFTLSAILGVDAQLQLLTSFLWMDLVWDNPFINWNPKECVGINKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRIKYDKPMRVTSICNLDIFYFPFDQQNCTFTFSSFLYTVDSMLLGMDKEVWEITDTSRKVIQTQGEWELLGINKATPKMSMGNNLYDQIMFYVAIRRRPSLYIINLLVPSSFLVAIDALSFYLPAESENRAPFKITLLLGYNVFLLMMNDLLPASGTPLISVYFALCLSLMVVSLLETVFITYLLHVATTQPPPMPRWLHSLLLHCTSPGRCCPTAPQKGNKGLGLTLTHLPGPKEPGELAGKKLGPRETEPDGGSGWTKTQLMELWVQFSHAMDTLLFRLYLLFMASSILTVIVLWNT
PTMs - Q8WXA8 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y234 | Phosphorylation | Uniprot | |
| T398 | Phosphorylation | Uniprot | |
| S404 | Phosphorylation | Uniprot | |
| T407 | Phosphorylation | Uniprot |
研究背景
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.
Cell membrane>Multi-pass membrane protein.
Note: Presumably retained within the endoplasmic reticulum unless complexed with HTR3A.
Expressed in many tissues including adult brain, colon, intestine, lung, muscle and stomach as well as fetal colon and kidney.
Forms a pentaheteromeric complex with HTR3A. Not functional as a homomeric complex.
Belongs to the ligand-gated ion channel (TC 1.A.9) family. 5-hydroxytryptamine receptor (TC 1.A.9.2) subfamily. HTR3C sub-subfamily.
研究領域
· Organismal Systems > Nervous system > Serotonergic synapse.
· Organismal Systems > Sensory system > Taste transduction.
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