製品: CCR8 Antibody
カタログ: DF10208
タンパク質の説明: Rabbit polyclonal antibody to CCR8
アプリケーション: WB IF/ICC
反応性: Human, Mouse
予測: Pig, Horse
分子量: 41 kDa, 50 kDa; 41kD(Calculated).
ユニプロット: P51685
RRID: AB_2840787

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 100ul $280 在庫あり
 200ul $350 在庫あり

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
予測:
Pig(100%), Horse(100%)
クローナリティ:
Polyclonal
特異性:
CCR8 Antibody detects endogenous levels of total CCR8.
RRID:
AB_2840787
引用形式: Affinity Biosciences Cat# DF10208, RRID:AB_2840787.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

C C chemokine receptor type 8; C C CKR 8; C C motif chemokine receptor 8; C-C chemokine receptor type 8; C-C CKR-8; CC chemokine receptor 8; CC chemokine receptor CHEMR1; CC chemokine receptor type 8; CC CKR 8; CC-CKR-8; CCR 8; CCR-8; Ccr8; CCR8 protein; CCR8-L; CCR8_HUMAN; CDw198; CDw198 antigen; Chemokine (C C motif) receptor 8; Chemokine (C C) receptor 8; Chemokine (C C) receptor like 2; Chemokine (CC motif) receptor 8; Chemokine (CC) receptor 8; Chemokine (CC) receptor like 1; Chemokine (CC) receptor like 2; Chemokine C C motif receptor 8; Chemokine C C receptor 8; Chemokine CC motif receptor 8; Chemokine CC receptor 8; Chemokine receptor 8; Chemokine receptor like 1; Chemokine receptor-like 1; CKR L1; CKR-L1; CKRL 1; CKRL1; CMKBR 8; CMKBR L2; CMKBR8; CMKBRL 2; CMKBRL2; CY 6; CY6; GPR CY6; GPR-CY6; GPRCY6; MGC123958; MGC123959; MGC129966; MGC129973; TER 1; TER1;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Sheep
63
Bovine
0
Dog
0
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P51685 基板として

Site PTM Type Enzyme
Y132 Phosphorylation
S334 Phosphorylation
S338 Phosphorylation
S339 Phosphorylation
S340 Phosphorylation

研究背景

機能:

Receptor for the chemokine CCL1/SCYA1/I-309. May regulate monocyte chemotaxis and thymic cell line apoptosis. Alternative coreceptor with CD4 for HIV-1 infection.

細胞の位置付け:

Cell membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
タンパク質ファミリー:

Belongs to the G-protein coupled receptor 1 family.

研究領域

· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction.   (View pathway)

· Human Diseases > Cancers: Overview > Viral carcinogenesis.

· Organismal Systems > Immune system > Chemokine signaling pathway.   (View pathway)

Restrictive clause

 

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For Research Use Only.
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