LT4R1 Antibody - #DF10223
製品: | LT4R1 Antibody |
カタログ: | DF10223 |
タンパク質の説明: | Rabbit polyclonal antibody to LT4R1 |
アプリケーション: | WB IHC |
反応性: | Human, Mouse, Rat, Monkey |
予測: | Horse, Rabbit, Dog |
分子量: | 38 kDa; 38kD(Calculated). |
ユニプロット: | Q15722 |
RRID: | AB_2840801 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF10223, RRID:AB_2840801.
折りたたみ/展開
BLT; BLT1; BLTR; Chemoattractant receptor-like 1; Chemokine receptor like 1; CMKRL1; G protein coupled receptor 16; G-protein coupled receptor 16; GPR16; Leukotriene B4 G Protein coupled receptor; Leukotriene B4 receptor 1; Leukotriene B4 receptor; LT4R1_HUMAN; LTB4 R 1; LTB4-R 1; LTB4-R1; LTB4R 1; Ltb4r; LTB4R1; LTBR1; P2RY7; P2Y purinoceptor 7; P2Y7; Purinergic receptor P2Y G protein coupled 7;
免疫原
Expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver. High level of expression in lymphoid tissues.
- Q15722 LT4R1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNLALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVARPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAFHLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVVNLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q15722 基板として
研究背景
Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
Phosphorylated by GRK6 upon leukotriene B4 binding; which promotes desensitization.
Cell membrane>Multi-pass membrane protein.
Expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver. High level of expression in lymphoid tissues.
Belongs to the G-protein coupled receptor 1 family.
研究領域
· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.
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