MSI1 Antibody - #DF2971
| 製品: | MSI1 Antibody |
| カタログ: | DF2971 |
| タンパク質の説明: | Rabbit polyclonal antibody to MSI1 |
| アプリケーション: | WB IHC |
| 反応性: | Human |
| 予測: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 39kDa; 39kD(Calculated). |
| ユニプロット: | O43347 |
| RRID: | AB_2840951 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF2971, RRID:AB_2840951.
折りたたみ／展開
Msi 1; Msi1; MSI1H_HUMAN; Musashi homolog 1; Musashi-1; Musashi1; RNA binding protein Musashi homolog 1; RNA-binding protein Musashi homolog 1;
免疫原
Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines.
- O43347 MSI1H_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
METDAPQPGLASPDSPHDPCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQSRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKQYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKMVECKKAQPKEVMSPTGSARGRSRVMPYGMDAFMLGIGMLGYPGFQATTYASRSYTGLAPGYTYQFPEFRVERTPLPSAPVLPELTAIPLTAYGPMAAAAAAAAVVRGTGSHPWTMAPPPGSTPSRTGGFLGTTSPGPMAELYGAANQDSGVSSYISAASPAPSTGFGHSLGGPLIATAFTNGYH
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O43347 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| S12 | Phosphorylation | Uniprot | |
| S15 | Phosphorylation | Uniprot | |
| K58 | Ubiquitination | Uniprot | |
| K76 | Ubiquitination | Uniprot | |
| S81 | Phosphorylation | Uniprot | |
| K93 | Ubiquitination | Uniprot | |
| K103 | Ubiquitination | Uniprot | |
| K144 | Ubiquitination | Uniprot | |
| S191 | Phosphorylation | Uniprot | |
| R197 | Methylation | Uniprot | |
| R199 | Methylation | Uniprot | |
| R201 | Methylation | Uniprot | |
| T251 | Phosphorylation | Uniprot | |
| S255 | Phosphorylation | Uniprot | |
| S312 | Phosphorylation | Uniprot | |
| S337 | Phosphorylation | Uniprot |
研究背景
RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-[GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity).
Cytoplasm. Nucleus.
Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines.
The first RNA recognition motif binds more strongly to RNA compared to the second one.
Belongs to the Musashi family.
研究領域
· Genetic Information Processing > Translation > mRNA surveillance pathway.
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