Prohibitin Antibody - #DF7600
製品: | Prohibitin Antibody |
カタログ: | DF7600 |
タンパク質の説明: | Rabbit polyclonal antibody to Prohibitin |
アプリケーション: | WB IHC |
反応性: | Human, Mouse, Rat |
予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
分子量: | 30 kDa; 30kD(Calculated). |
ユニプロット: | P35232 |
RRID: | AB_2841091 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF7600, RRID:AB_2841091.
折りたたみ/展開
Epididymis luminal protein 215; Epididymis secretory sperm binding protein Li 54e; HEL 215; HEL S 54e; PHB; PHB_HUMAN; PHB1; Prohibitin;
免疫原
- P35232 PHB_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDIVVGEGTHFLIPWVQKPIIFDCRSRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAGQSVLLQLPQ
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P35232 基板として
Site | PTM Type | Enzyme | Source |
---|---|---|---|
A2 | Acetylation | Uniprot | |
K4 | Acetylation | Uniprot | |
K4 | Methylation | Uniprot | |
K4 | Ubiquitination | Uniprot | |
K11 | Methylation | Uniprot | |
R41 | Methylation | Uniprot | |
S82 | Phosphorylation | Uniprot | |
K83 | Ubiquitination | Uniprot | |
T91 | Phosphorylation | Uniprot | |
R93 | Methylation | Uniprot | |
S101 | Phosphorylation | Uniprot | |
T108 | Phosphorylation | Uniprot | |
S109 | Phosphorylation | Uniprot | |
Y114 | Phosphorylation | P06213 (INSR) | Uniprot |
S121 | O-Glycosylation | Uniprot | |
T123 | Phosphorylation | Uniprot | |
K128 | Acetylation | Uniprot | |
K128 | Ubiquitination | Uniprot | |
S151 | Phosphorylation | Uniprot | |
K177 | Ubiquitination | Uniprot | |
K186 | Ubiquitination | Uniprot | |
K202 | Acetylation | Uniprot | |
K202 | Ubiquitination | Uniprot | |
K207 | Acetylation | Uniprot | |
K208 | Ubiquitination | Uniprot | |
S213 | Phosphorylation | Uniprot | |
S218 | Phosphorylation | Uniprot | |
K219 | Ubiquitination | Uniprot | |
K240 | Ubiquitination | Uniprot | |
Y249 | Phosphorylation | Uniprot | |
S252 | Phosphorylation | Uniprot | |
S254 | Phosphorylation | Uniprot | |
T258 | O-Glycosylation | Uniprot | |
T258 | Phosphorylation | P31749 (AKT1) | Uniprot |
Y259 | Phosphorylation | Uniprot | |
S265 | Phosphorylation | Uniprot |
研究背景
Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging.
Mitochondrion inner membrane. Nucleus.
Widely expressed in different tissues.
Interacts with PHB2. Interacts with STOML2.
Belongs to the prohibitin family.
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