製品: FKBPL Antibody
カタログ: AF0446
タンパク質の説明: Rabbit polyclonal antibody to FKBPL
アプリケーション: WB IF/ICC
反応性: Human, Mouse, Rat
予測: Bovine, Sheep, Rabbit, Xenopus
分子量: 50-70kDa; 38kD(Calculated).
ユニプロット: Q9UIM3
RRID: AB_2834392

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Bovine(100%), Sheep(100%), Rabbit(100%), Xenopus(88%)
クローナリティ:
Polyclonal
特異性:
FKBPL Antibody detects endogenous levels of total FKBPL.
RRID:
AB_2834392
引用形式: Affinity Biosciences Cat# AF0446, RRID:AB_2834392.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

DIR1; FK506 binding protein like; FK506-binding protein-like; Fkbpl; FKBPL_HUMAN; NG7; OTTHUMP00000029170; WAF 1/CIP1 stabilizing protein 39; WAF-1/CIP1 stabilizing protein 39; WISP39;

免疫原

免疫原:

A synthesized peptide derived from human FKBPL, corresponding to a region within the internal amino acids.

Uniprot:
遺伝子(ID):
発現特異性:
Q9UIM3 FKBPL_HUMAN:

Ubiquitously expressed with higher levels in testis.

タンパク質の説明:
FKBPL May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21. Forms a ternary complex with CDKN1A/p21 and HSP90AB1/Hsp90.
タンパク質配列:
METPPVNTIGEKDTSQPQQEWEKNLRENLDSVIQIRQQPRDPPTETLELEVSPDPASQILEHTQGAEKLVAELEGDSHKSHGSTSQMPEALQASDLWYCPDGSFVKKIVIRGHGLDKPKLGSCCRVLALGFPFGSGPPEGWTELTMGVGPWREETWGELIEKCLESMCQGEEAELQLPGHSGPPVRLTLASFTQGRDSWELETSEKEALAREERARGTELFRAGNPEGAARCYGRALRLLLTLPPPGPPERTVLHANLAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKNRAAQEELGKVVIQGKNQDAGLAQGLRKMFG

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Bovine
100
Sheep
100
Rabbit
100
Xenopus
88
Pig
0
Horse
0
Dog
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

研究背景

機能:

May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21.

組織特異性:

Ubiquitously expressed with higher levels in testis.

Restrictive clause

 

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