ARHGAP5 Antibody - #DF7649
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF7649, RRID:AB_2841126.
折りたたみ／展開
ARHGAP 5; ARHGAP5; p190 B; p190 RhoGAP; Rho GTPase activating protein 5; RhoGAP 5; RhoGAP; RhoGAP5;
免疫原
- Q13017 RHG05_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MMAKNKEPRPPSYTISIVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTIDFGGRVVNNDHFLYWGDIIQNSEDGVECKIHVIEQTEFIDDQTFLPHRSTNLQPYIKRAAASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFVNNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNKKNLLVVETSARFNVNIETCFTALVQMLDKTRSKPKIIPYLDAYKTQRQLVVTATDKFEKLVQTVRDYHATWKTVSNKLKNHPDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYINTLPRAFNTLLPNLEEIEHLNWSEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRRIPFDLLSTLEAEKVYQNHVQHLISEKRRVEMKEKFKKTLEKIQFISPGQPWEEVMCFVMEDEAYKYITEADSKEVYGRHQREIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRESLLLKHIGFVYHPTKETCLSGQNCTDIKVEQLLASSLLQLDHGRLRLYHDSTNIDKVNLFILGKDGLAQELANEIRTQSTDDEYALDGKIYELDLRPVDAKSPYFLSQLWTAAFKPHGCFCVFNSIESLSFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQRDSISKNLPILRHQGQQLANKLQCPFVDVPAGTYPRKFNETQIKQALRGVLESVKHNLDVVSPIPANKDLSEADLRIVMCAMCGDPFSVDLILSPFLDSHSCSAAQAGQNNSLMLDKIIGEKRRRIQITILSYHSSIGVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFENEAIKELMTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSDNTRESTHQSEDVFLPSPRDCFPYNNYPDSDDDTEAPPPYSPIGDDVQLLPTPSDRSRYRLDLEGNEYPIHSTPNCHDHERNHKVPPPIKPKPVVPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLAHPEDMDPSDNYAEPIDTIFKQKGYSDEIYVVPDDSQNRIKIRNSFVNNTQGDEENGFSDRTSKSHGERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFTTSKTKRKGRHRGSEEDPLLSPVETWKGGIDNPAITSDQELDDKKMKKKTHKVKEDKKQKKKTKNFNPPTRRNWESNYFGMPLQDLVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVETFIQQCQFFFYNGEIVETTNIVAPPPPSNPGQLVEPMVPLQLPPPLQPQLIQPQLQTDPLGII
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q13017 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S12 | Phosphorylation | Uniprot | |
| S16 | Phosphorylation | Uniprot | |
| S21 | Phosphorylation | Uniprot | |
| T23 | Phosphorylation | Uniprot | |
| T199 | Phosphorylation | Uniprot | |
| T289 | Phosphorylation | Uniprot | |
| Y306 | Phosphorylation | P06213 (INSR) | Uniprot |
| K314 | Acetylation | Uniprot | |
| K321 | Acetylation | Uniprot | |
| K327 | Ubiquitination | Uniprot | |
| K394 | Ubiquitination | Uniprot | |
| K533 | Ubiquitination | Uniprot | |
| S540 | Phosphorylation | Uniprot | |
| S590 | Phosphorylation | Uniprot | |
| T591 | Phosphorylation | Uniprot | |
| K724 | Ubiquitination | Uniprot | |
| S765 | Phosphorylation | Uniprot | |
| S862 | Phosphorylation | Uniprot | |
| S948 | Phosphorylation | Uniprot | |
| S951 | Phosphorylation | Uniprot | |
| S968 | Phosphorylation | Uniprot | |
| S981 | Phosphorylation | Uniprot | |
| Y1019 | Phosphorylation | Uniprot | |
| T1024 | Phosphorylation | Uniprot | |
| K1053 | Ubiquitination | Uniprot | |
| K1060 | Ubiquitination | Uniprot | |
| S1088 | Phosphorylation | Uniprot | |
| Y1091 | Phosphorylation | Uniprot | |
| K1102 | Ubiquitination | Uniprot | |
| Y1104 | Phosphorylation | Uniprot | |
| S1105 | Phosphorylation | Uniprot | |
| Y1109 | Phosphorylation | P12931 (SRC) , Q13882 (PTK6) | Uniprot |
| S1115 | Phosphorylation | Uniprot | |
| S1124 | Phosphorylation | Uniprot | |
| T1129 | Phosphorylation | Uniprot | |
| S1138 | Phosphorylation | Uniprot | |
| T1159 | Phosphorylation | Uniprot | |
| T1171 | Phosphorylation | Uniprot | |
| S1173 | Phosphorylation | Uniprot | |
| S1176 | Phosphorylation | Uniprot | |
| S1184 | Phosphorylation | Uniprot | |
| S1195 | Phosphorylation | Uniprot | |
| S1202 | Phosphorylation | Uniprot | |
| T1206 | Phosphorylation | Uniprot | |
| T1217 | Phosphorylation | Uniprot | |
| S1218 | Phosphorylation | Uniprot | |
| S1396 | Phosphorylation | Uniprot |
研究背景
GTPase-activating protein for Rho family members.
Cytoplasm. Cell membrane>Peripheral membrane protein.
Note: Also membrane-associated in a fibrillar pattern that colocalizes with the alpha5-beta1 integrin receptor (ITGA5/ITGB1) for fibronectin.
Detected in skin fibroblasts (at protein level).
May interact with RASA1/p120GAP.
The pG1 pseudoGTPase domain does not bind GTP.
研究領域
· Cellular Processes > Cellular community - eukaryotes > Focal adhesion. (View pathway)
· Organismal Systems > Immune system > Leukocyte transendothelial migration. (View pathway)
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