TGIF1 Antibody - #DF7689
| 製品: | TGIF1 Antibody |
| カタログ: | DF7689 |
| タンパク質の説明: | Rabbit polyclonal antibody to TGIF1 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus |
| 分子量: | 45 kDa; 43kD(Calculated). |
| ユニプロット: | Q15583 |
| RRID: | AB_2841160 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF7689, RRID:AB_2841160.
折りたたみ／展開
5' TG 3' interacting factor; 5''-TG-3''-interacting factor 1; Homeobox protein TGIF; Homeobox protein TGIF1; HPE4; MGC39747; MGC5066; TALE homeobox TG-interacting factor; TG interacting factor isoform c; TG-interacting factor; TGFB induced factor; TGFB-induced factor homeobox 1; TGIF1; TGIF1_HUMAN; transforming growth factor-beta-induced factor;
免疫原
- Q15583 TGIF1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MVLAQSRVSAGVGSPHCSGSGGGGSDSFPWPASHPGNPQCSFSTAFLASPRLSRGTLAYLPPAPWSSLATPSALLGSSCAPPPPPARCPQPRALSPELGTKAGPRRPHRWELPRSPSQGAQGPAPRRRLLETMKGIVAASGSETEDEDSMDIPLDLSSSAGSGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLPDMLRKDGKDPNQFTISRRGAKISETSSVESVMGIKNFMPALEETPFHSCTAGPNPTLGRPLSPKPSSPGSVLARPSVICHTTVTALKDVPFSLCQSVGVGQNTDIQQIAAKNFTDTSLMYPEDTCKSGPSTNTQSGLFNTPPPTPPDLNQDFSGFQLLVDVALKRAAEMELQAKLTA
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q15583 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S95 | Phosphorylation | Uniprot | |
| S115 | Phosphorylation | Uniprot | |
| S140 | Phosphorylation | Uniprot | |
| S142 | Phosphorylation | Uniprot | |
| T144 | Phosphorylation | Uniprot | |
| K232 | Ubiquitination | Uniprot | |
| S251 | Phosphorylation | Uniprot | |
| S286 | Phosphorylation | Uniprot | |
| S291 | Phosphorylation | Uniprot | |
| S294 | Phosphorylation | Uniprot |
研究背景
Binds to a retinoid X receptor (RXR) responsive element from the cellular retinol-binding protein II promoter (CRBPII-RXRE). Inhibits the 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element. Active transcriptional corepressor of SMAD2. Links the nodal signaling pathway to the bifurcation of the forebrain and the establishment of ventral midline structures. May participate in the transmission of nuclear signals during development and in the adult, as illustrated by the down-modulation of the RXR alpha activities.
Nucleus.
Interacts with CTBP, SMAD2, SMAD3 and HDAC1.
Belongs to the TALE/TGIF homeobox family.
研究領域
· Environmental Information Processing > Signal transduction > TGF-beta signaling pathway. (View pathway)
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