製品: ILP2 Antibody
カタログ: DF7725
タンパク質の説明: Rabbit polyclonal antibody to ILP2
アプリケーション: WB
反応性: Human, Mouse, Rat
分子量: 33 kDa; 27kD(Calculated).
ユニプロット: Q96P09
RRID: AB_2841193

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 100ul $280 在庫あり
 200ul $350 在庫あり

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Polyclonal
特異性:
ILP2 Antibody detects endogenous levels of total ILP2.
RRID:
AB_2841193
引用形式: Affinity Biosciences Cat# DF7725, RRID:AB_2841193.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Baculoviral IAP repeat containing 8; Baculoviral IAP repeat containing protein 8; Baculoviral IAP repeat-containing protein 8; BIRC 8; BIRC8; BIRC8 protein; BIRC8_HUMAN; hILP 2; hILP2; IAP like protein 2; IAP-like protein 2; ILP 2; ILP-2; Inhibitor of apoptosis like protein 2; Inhibitor of apoptosis-like protein 2; Testis specific inhibitor of apoptosis; Testis-specific inhibitor of apoptosis;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q96P09 BIRC8_HUMAN:

Testis specific in normal tissues.

タンパク質配列:
MTGYEARLITFGTWMYSVNKEQLARAGFYAIGQEDKVQCFHCGGGLANWKPKEDPWEQHAKWYPGCKYLLEEKGHEYINNIHLTRSLEGALVQTTKKTPSLTKRISDTIFPNPMLQEAIRMGFDFKDVKKIMEERIQTSGSNYKTLEVLVADLVSAQKDTTENELNQTSLQREISPEEPLRRLQEEKLCKICMDRHIAVVFIPCGHLVTCKQCAEAVDRCPMCSAVIDFKQRVFMS

PTMs - Q96P09 基板として

Site PTM Type Enzyme
S155 Phosphorylation
K187 Ubiquitination

研究背景

機能:

Protects against apoptosis mediated by BAX.

細胞の位置付け:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Testis specific in normal tissues.

サブユニット構造:

Binds to caspase-9.

タンパク質ファミリー:

Belongs to the IAP family.

研究領域

· Cellular Processes > Cell growth and death > Apoptosis - multiple species.   (View pathway)

· Genetic Information Processing > Folding, sorting and degradation > Ubiquitin mediated proteolysis.   (View pathway)

· Human Diseases > Infectious diseases: Parasitic > Toxoplasmosis.

· Human Diseases > Cancers: Overview > Pathways in cancer.   (View pathway)

· Human Diseases > Cancers: Specific types > Small cell lung cancer.   (View pathway)

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.