PPT1 Antibody - #DF7733
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF7733, RRID:AB_2841201.
折りたたみ／展開
Ceroid palmitoyl palmitoyl protein thioesterase 1; CLN1; EC 3.1.2.22; INCL; Palmitoyl protein hydrolase 1; Palmitoyl protein thioesterase 1; Palmitoyl-protein hydrolase 1; Palmitoyl-protein thioesterase 1; PPT; PPT-1; PPT1; PPT1_HUMAN;
免疫原
- P50897 PPT1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MASPGCLWLLAVALLPWTCASRALQHLDPPAPLPLVIWHGMGDSCCNPLSMGAIKKMVEKKIPGIYVLSLEIGKTLMEDVENSFFLNVNSQVTTVCQALAKDPKLQQGYNAMGFSQGGQFLRAVAQRCPSPPMINLISVGGQHQGVFGLPRCPGESSHICDFIRKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKNLMALKKFVMVKFLNDSIVDPVDSEWFGFYRSGQAKETIPLQETSLYTQDRLGLKEMDNAGQLVFLATEGDHLQLSEEWFYAHIIPFLG
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P50897 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y66 | Phosphorylation | Uniprot | |
| S69 | Phosphorylation | Uniprot | |
| K165 | Ubiquitination | Uniprot | |
| Y172 | Phosphorylation | Uniprot | |
| K174 | Ubiquitination | Uniprot | |
| Y185 | Phosphorylation | Uniprot | |
| K191 | Ubiquitination | Uniprot | |
| N197 | N-Glycosylation | Uniprot | |
| N212 | N-Glycosylation | Uniprot | |
| K216 | Ubiquitination | Uniprot | |
| K224 | Acetylation | Uniprot | |
| N232 | N-Glycosylation | Uniprot | |
| K253 | Ubiquitination | Uniprot | |
| Y264 | Phosphorylation | Uniprot |
研究背景
Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons.
Glycosylated.
Lysosome. Secreted.
Interacts with CLN5. Interacts with ATP5F1A and ATP5F1B (By similarity).
Belongs to the palmitoyl-protein thioesterase family.
研究領域
· Cellular Processes > Transport and catabolism > Lysosome. (View pathway)
· Metabolism > Lipid metabolism > Fatty acid elongation.
· Metabolism > Global and overview maps > Metabolic pathways.
· Metabolism > Global and overview maps > Fatty acid metabolism.
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