FGF3 Antibody - #DF7761
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF7761, RRID:AB_2841227.
折りたたみ／展開
FGF 3; Fibroblast growth factor 3; HBGF 3; HBGF3; INT 2; INT 2 proto oncogene protein; INT 2 proto oncogene protein precurosr; INT2; INT2 proto oncogene protein precurosr; Murine mammary tumor virus integration site (v int 2) oncogene homolog; Murine mammary tumor virus integration site 2; Oncogene INT2; V INT2 murine mammary tumor virus integration site oncogene homolog;
免疫原
- P11487 FGF3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGLIWLLLLSLLEPGWPAAGPGARLRRDAGGRGGVYEHLGGAPRRRKLYCATKYHLQLHPSGRVNGSLENSAYSILEITAVEVGIVAIRGLFSGRYLAMNKRGRLYASEHYSAECEFVERIHELGYNTYASRLYRTVSSTPGARRQPSAERLWYVSVNGKGRPRRGFKTRRTQKSSLFLPRVLDHRDHEMVRQLQSGLPRPPGKGVQPRRRRQKQSPDNLEPSHVQASRLGSQLEASAH
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P11487 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| R32 | Methylation | Uniprot | |
| R44 | Methylation | Uniprot | |
| R45 | Methylation | Uniprot | |
| S93 | Phosphorylation | Uniprot | |
| Y96 | Phosphorylation | Uniprot | |
| T136 | Phosphorylation | Uniprot | |
| S138 | Phosphorylation | Uniprot | |
| S139 | Phosphorylation | Uniprot | |
| S176 | Phosphorylation | Uniprot |
研究背景
Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Required for normal ear development.
Secreted.
Interacts with FGFR1 and FGFR2. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors.
Belongs to the heparin-binding growth factors family.
研究領域
· Cellular Processes > Cell motility > Regulation of actin cytoskeleton. (View pathway)
· Environmental Information Processing > Signal transduction > MAPK signaling pathway. (View pathway)
· Environmental Information Processing > Signal transduction > Ras signaling pathway. (View pathway)
· Environmental Information Processing > Signal transduction > Rap1 signaling pathway. (View pathway)
· Environmental Information Processing > Signal transduction > PI3K-Akt signaling pathway. (View pathway)
· Human Diseases > Cancers: Overview > Pathways in cancer. (View pathway)
· Human Diseases > Cancers: Specific types > Melanoma. (View pathway)
· Human Diseases > Cancers: Specific types > Breast cancer. (View pathway)
· Human Diseases > Cancers: Specific types > Gastric cancer. (View pathway)
Restrictive clause
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For Research Use Only.
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