SOAT1 Antibody - #DF7778
| 製品: | SOAT1 Antibody |
| カタログ: | DF7778 |
| タンパク質の説明: | Rabbit polyclonal antibody to SOAT1 |
| アプリケーション: | WB IHC |
| 反応性: | Human, Rat |
| 予測: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 65 kDa; 65kD(Calculated). |
| ユニプロット: | P35610 |
| RRID: | AB_2841242 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF7778, RRID:AB_2841242.
折りたたみ／展開
ACACT; ACAT; ACAT-1; ACAT1; Acyl coenzyme A cholesterol acyltransferase 1; Acyl-coenzyme A:cholesterol acyltransferase 1; Cholesterol acyltransferase 1; SOAT; SOAT1; SOAT1_HUMAN; STAT; Sterol O acyltransferase 1; Sterol O-acyltransferase 1;
免疫原
- P35610 SOAT1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MVGEEKMSLRNRLSKSRENPEEDEDQRNPAKESLETPSNGRIDIKQLIAKKIKLTAEAEELKPFFMKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSVLEGEKNNHRAKDLRAPPEQGKIFIARRSLLDELLEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFSLLSYAFGKFPTVVWTWWIMFLSTFSVPYFLFQHWATGYSKSSHPLIRSLFHGFLFMIFQIGVLGFGPTYVVLAYTLPPASRFIIIFEQIRFVMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRNPTVRWGYVAMKFAQVFGCFFYVYYIFERLCAPLFRNIKQEPFSARVLVLCVFNSILPGVLILFLTFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYAYKDFLWFFSKRFKSAAMLAVFAVSAVVHEYALAVCLSFFYPVLFVLFMFFGMAFNFIVNDSRKKPIWNVLMWTSLFLGNGVLLCFYSQEWYARQHCPLKNPTFLDYVRPRSWTCRYVF
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P35610 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| S8 | Phosphorylation | Uniprot | |
| S14 | Phosphorylation | Uniprot | |
| S16 | Phosphorylation | Uniprot | |
| K31 | Ubiquitination | Uniprot | |
| S33 | Phosphorylation | Uniprot | |
| T36 | Phosphorylation | Uniprot | |
| S38 | Phosphorylation | Uniprot | |
| K45 | Ubiquitination | Uniprot | |
| K62 | Ubiquitination | Uniprot | |
| K67 | Ubiquitination | Uniprot | |
| S71 | Phosphorylation | Uniprot | |
| K83 | Ubiquitination | Uniprot | |
| K104 | Ubiquitination | Uniprot | |
| K120 | Ubiquitination | Uniprot | |
| K283 | Ubiquitination | Uniprot | |
| K353 | Ubiquitination | Uniprot | |
| K531 | Ubiquitination | Uniprot |
研究背景
Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol. Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase.
Endoplasmic reticulum membrane>Multi-pass membrane protein.
May form homo- or heterodimers. Interacts with UBIAD1.
Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
研究領域
· Metabolism > Lipid metabolism > Steroid biosynthesis.
· Organismal Systems > Digestive system > Cholesterol metabolism.
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