Cytokeratin 6a Antibody - #DF7789
| 製品: | Cytokeratin 6a Antibody |
| カタログ: | DF7789 |
| タンパク質の説明: | Rabbit polyclonal antibody to Cytokeratin 6a |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Bovine, Dog |
| 分子量: | 60 kDa; 60kD(Calculated). |
| ユニプロット: | P02538 |
| RRID: | AB_2841246 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF7789, RRID:AB_2841246.
折りたたみ／展開
CK-6A;CK-6D;CK6A;CK6D;Cytokeratin-6A;Cytokeratin-6D;K2C6A_HUMAN;K6A;K6D;keratin 6A;Keratin;Keratin, type II cytoskeletal 6A;Keratin-6A;Krt6a;KRT6D;type II cytoskeletal 6A;Type-II keratin Kb6;
免疫原
Constitutively expressed in distinct types of epithelia such as those in oral mucosa, esophagus, papillae of tongue and hair follicle outer root sheath.
- P02538 K2C6A_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MASTSTTIRSHSSSRRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRGMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAIGGGLSSVGGGSSTIKYTTTSSSSRKSYKH
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P02538 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S3 | Phosphorylation | Uniprot | |
| S5 | Phosphorylation | Uniprot | |
| S10 | Phosphorylation | Uniprot | |
| S19 | Phosphorylation | Uniprot | |
| S22 | Phosphorylation | Uniprot | |
| S31 | Phosphorylation | Uniprot | |
| S34 | Phosphorylation | Uniprot | |
| S37 | Phosphorylation | Uniprot | |
| S41 | Phosphorylation | Uniprot | |
| R42 | Methylation | Uniprot | |
| S44 | Phosphorylation | Uniprot | |
| S58 | Phosphorylation | Uniprot | |
| S60 | Phosphorylation | Uniprot | |
| Y62 | Phosphorylation | Uniprot | |
| S67 | Phosphorylation | Uniprot | |
| S71 | Phosphorylation | Uniprot | |
| S76 | Phosphorylation | Uniprot | |
| S80 | Phosphorylation | Uniprot | |
| Y83 | Phosphorylation | Uniprot | |
| S85 | Phosphorylation | Uniprot | |
| K168 | Ubiquitination | Uniprot | |
| T169 | Phosphorylation | Uniprot | |
| K173 | Acetylation | Uniprot | |
| K173 | Methylation | Uniprot | |
| K173 | Sumoylation | Uniprot | |
| K173 | Ubiquitination | Uniprot | |
| S176 | Phosphorylation | Uniprot | |
| K180 | Acetylation | Uniprot | |
| K180 | Ubiquitination | Uniprot | |
| K194 | Ubiquitination | Uniprot | |
| K204 | Ubiquitination | Uniprot | |
| Y217 | Phosphorylation | Uniprot | |
| S237 | Phosphorylation | Uniprot | |
| K252 | Methylation | Uniprot | |
| K252 | Ubiquitination | Uniprot | |
| Y253 | Phosphorylation | Uniprot | |
| K259 | Methylation | Uniprot | |
| K259 | Ubiquitination | Uniprot | |
| Y278 | Phosphorylation | Uniprot | |
| T290 | Phosphorylation | Uniprot | |
| Y302 | Phosphorylation | Uniprot | |
| S332 | Phosphorylation | Uniprot | |
| Y341 | Phosphorylation | Uniprot | |
| S348 | Phosphorylation | Uniprot | |
| Y356 | Phosphorylation | Uniprot | |
| T358 | Phosphorylation | Uniprot | |
| Y360 | Phosphorylation | Uniprot | |
| T366 | Phosphorylation | Uniprot | |
| S393 | Phosphorylation | Uniprot | |
| K426 | Acetylation | Uniprot | |
| Y448 | Phosphorylation | Uniprot | |
| R475 | Methylation | Uniprot | |
| S540 | Phosphorylation | Uniprot | |
| S541 | Phosphorylation | Uniprot | |
| S546 | Phosphorylation | Uniprot | |
| K550 | Methylation | Uniprot | |
| Y551 | Phosphorylation | Uniprot | |
| T552 | Phosphorylation | Uniprot | |
| S557 | Phosphorylation | Uniprot | |
| S558 | Phosphorylation | Uniprot | |
| S561 | Phosphorylation | Uniprot |
研究背景
Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair.
Constitutively expressed in distinct types of epithelia such as those in oral mucosa, esophagus, papillae of tongue and hair follicle outer root sheath.
Heterodimer of a type I and a type II keratin. KRT6 isomers associate with KRT16 and/or KRT17 (By similarity). Interacts with TCHP.
Belongs to the intermediate filament family.
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