製品: SULT1A3 Antibody
カタログ: DF7889
タンパク質の説明: Rabbit polyclonal antibody to SULT1A3
アプリケーション: WB IHC
反応性: Human
分子量: 34 kDa; 34kD(Calculated).
ユニプロット: P0DMN0
RRID: AB_2841310

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Polyclonal
特異性:
SULT1A3 Antibody detects endogenous levels of total SULT1A3.
RRID:
AB_2841310
引用形式: Affinity Biosciences Cat# DF7889, RRID:AB_2841310.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
P0DMN0 ST1A4_HUMAN:

Liver, colon, kidney, lung, brain, spleen, small intestine, placenta and leukocyte.

タンパク質配列:
MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLINTYPKSGTTWVSQILDMIYQGGDLEKCNRAPIYVRVPFLEVNDPGEPSGLETLKDTPPPRLIKSHLPLALLPQTLLDQKVKVVYVARNPKDVAVSYYHFHRMEKAHPEPGTWDSFLEKFMAGEVSYGSWYQHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETMDFMVQHTSFKEMKKNPMTNYTTVPQELMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL

PTMs - P0DMN0 基板として

Site PTM Type Enzyme
K16 Ubiquitination
K97 Ubiquitination
K106 Ubiquitination
K122 Ubiquitination
K124 Ubiquitination
S253 Phosphorylation
K283 Ubiquitination

研究背景

機能:

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, norepinephrine and serotonin) and phenolic and catechol drugs.

PTMs:

The N-terminus is blocked.

細胞の位置付け:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Liver, colon, kidney, lung, brain, spleen, small intestine, placenta and leukocyte.

サブユニット構造:

Homodimer.

タンパク質ファミリー:

Belongs to the sulfotransferase 1 family.

研究領域

· Human Diseases > Cancers: Overview > Chemical carcinogenesis.

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