CD2 Antibody - #DF7894
| 製品: | CD2 Antibody |
| カタログ: | DF7894 |
| タンパク質の説明: | Rabbit polyclonal antibody to CD2 |
| アプリケーション: | WB |
| 反応性: | Human |
| 分子量: | 39 kDa; 39kD(Calculated). |
| ユニプロット: | P06729 |
| RRID: | AB_2841315 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF7894, RRID:AB_2841315.
折りたたみ／展開
CD 2; CD2; CD2 antigen (p50), sheep red blood cell receptor; CD2 antigen; CD2 molecule; CD2_HUMAN; Erythrocyte receptor; FLJ46032; LFA-2; LFA-3 receptor; LFA2; LFA3 receptor; Ly-37; Lymphocyte function antigen 2; lymphocyte-function antigen-2; OTTHUMP00000024366; Rosette receptor; Sheep erythrocyte receptor; SRBC; T cell surface antigen CD2; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5; T-lymphocyte surface CD2 antigen; T11;
免疫原
- P06729 CD2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSFPCKFVASFLLIFNVSSKGAVSKEITNALETWGALGQDINLDIPSFQMSDDIDDIKWEKTSDKKKIAQFRKEKETFKEKDTYKLFKNGTLKIKHLKTDDQDIYKVSIYDTKGKNVLEKIFDLKIQERVSKPKISWTCINTTLTCEVMNGTDPELNLYQDGKHLKLSQRVITHKWTTSLSAKFKCTAGNKVSKESSVEPVSCPEKGLDIYLIIGICGGGSLLMVFVALLVFYITKRKKQRSRRNDEELETRAHRVATEERGRKPHQIPASTPQNPATSQHPPPPPGHRSQAPSHRPPPPGHRVQHQPQKRPPAPSGTQVHQQKGPPLPRPRVQPKPPHGAAENSLSPSSN
PTMs - P06729 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| N89 | N-Glycosylation | Uniprot | |
| T99 | Phosphorylation | Uniprot | |
| K106 | Ubiquitination | Uniprot | |
| K125 | Ubiquitination | Uniprot | |
| N141 | N-Glycosylation | Uniprot | |
| N150 | N-Glycosylation | Uniprot | |
| K166 | Ubiquitination | Uniprot | |
| T173 | Phosphorylation | Uniprot | |
| T258 | Phosphorylation | Uniprot | |
| K264 | Ubiquitination | Uniprot | |
| S290 | Phosphorylation | Uniprot | |
| S294 | Phosphorylation | Uniprot | |
| K310 | Ubiquitination | Uniprot | |
| K324 | Ubiquitination | Uniprot | |
| S345 | Phosphorylation | Uniprot | |
| S347 | Phosphorylation | Uniprot | |
| S350 | Phosphorylation | Uniprot |
研究背景
CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
Cell membrane>Single-pass type I membrane protein.
Interacts with CD48 (By similarity). Interacts with CD58 (LFA-3). Interacts with CD2AP (By similarity). Interacts with PSTPIP1.
研究領域
· Environmental Information Processing > Signaling molecules and interaction > Cell adhesion molecules (CAMs). (View pathway)
· Organismal Systems > Immune system > Hematopoietic cell lineage. (View pathway)
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.