AGTR2 Antibody - #DF7928
| 製品: | AGTR2 Antibody |
| カタログ: | DF7928 |
| タンパク質の説明: | Rabbit polyclonal antibody to AGTR2 |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Rabbit, Dog |
| 分子量: | 41 kDa; 41kD(Calculated). |
| ユニプロット: | P50052 |
| RRID: | AB_2841340 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF7928, RRID:AB_2841340.
折りたたみ／展開
AGTR 2; Agtr2; AGTR2_HUMAN; angiotensin II receptor type 2; Angiotensin II type-2 receptor; Angiotensin receptor 2; AT 2; AT2; ATGR 2; ATGR2; MRX 88; MRX88; Type 2 angiotensin II receptor; Type-2 angiotensin II receptor;
免疫原
In adult, highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. Expressed in the cerebellum. Very highly expressed in fetal kidney and intestine.
- P50052 AGTR2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKGNSTLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRESMSCRKSSSLREMETFVS
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P50052 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K203 | Acetylation | Uniprot | |
| S331 | Phosphorylation | Uniprot |
研究背景
Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.
Cell membrane>Multi-pass membrane protein.
In adult, highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. Expressed in the cerebellum. Very highly expressed in fetal kidney and intestine.
Interacts with MTUS1.
Belongs to the G-protein coupled receptor 1 family.
研究領域
· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.
· Organismal Systems > Circulatory system > Adrenergic signaling in cardiomyocytes. (View pathway)
· Organismal Systems > Endocrine system > Renin-angiotensin system. (View pathway)
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