UGGT1 Antibody - #DF8205
| 製品: | UGGT1 Antibody |
| カタログ: | DF8205 |
| タンパク質の説明: | Rabbit polyclonal antibody to UGGT1 |
| アプリケーション: | WB IHC |
| 反応性: | Human |
| 予測: | Pig, Zebrafish, Bovine, Horse, Dog |
| 分子量: | 177 kDa; 177kD(Calculated). |
| ユニプロット: | Q9NYU2 |
| RRID: | AB_2841513 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF8205, RRID:AB_2841513.
折りたたみ／展開
GT; HUGT1; UDP glucose glycoprotein glucosyltransferase 1; UDP Glucose Glycoprotein Glucosyltransferase; UDP--Glc:glycoprotein glucosyltransferase; UDP-glucose ceramide glucosyltransferase-like 1; UDP-glucose:glycoprotein glucosyltransferase 1; UGCGL1; UGGG1; UGGG1_HUMAN; UGGT; Uggt1; UGT1; UGTR;
免疫原
Higher levels in pancreas, skeletal muscle, kidney, and brain. Low levels in lung and heart.
- Q9NYU2 UGGG1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGCKGDASGACAAGALPVTGVCYKMGVLVVLTVLWLFSSVKADSKAITTSLTTKWFSTPLLLEASEFLAEDSQEKFWNFVEASQNIGSSDHDGTDYSYYHAILEAAFQFLSPLQQNLFKFCLSLRSYSATIQAFQQIAADEPPPEGCNSFFSVHGKKTCESDTLEALLLTASERPKPLLFKGDHRYPSSNPESPVVIFYSEIGSEEFSNFHRQLISKSNAGKINYVFRHYIFNPRKEPVYLSGYGVELAIKSTEYKAKDDTQVKGTEVNTTVIGENDPIDEVQGFLFGKLRDLHPDLEGQLKELRKHLVESTNEMAPLKVWQLQDLSFQTAARILASPVELALVVMKDLSQNFPTKARAITKTAVSSELRTEVEENQKYFKGTLGLQPGDSALFINGLHMDLDTQDIFSLFDVLRNEARVMEGLHRLGIEGLSLHNVLKLNIQPSEADYAVDIRSPAISWVNNLEVDSRYNSWPSSLQELLRPTFPGVIRQIRKNLHNMVFIVDPAHETTAELMNTAEMFLSNHIPLRIGFIFVVNDSEDVDGMQDAGVAVLRAYNYVAQEVDDYHAFQTLTHIYNKVRTGEKVKVEHVVSVLEKKYPYVEVNSILGIDSAYDRNRKEARGYYEQTGVGPLPVVLFNGMPFEREQLDPDELETITMHKILETTTFFQRAVYLGELPHDQDVVEYIMNQPNVVPRINSRILTAERDYLDLTASNNFFVDDYARFTILDSQGKTAAVANSMNYLTKKGMSSKEIYDDSFIRPVTFWIVGDFDSPSGRQLLYDAIKHQKSSNNVRISMINNPAKEISYENTQISRAIWAALQTQTSNAAKNFITKMAKEGAAEALAAGADIAEFSVGGMDFSLFKEVFESSKMDFILSHAVYCRDVLKLKKGQRAVISNGRIIGPLEDSELFNQDDFHLLENIILKTSGQKIKSHIQQLRVEEDVASDLVMKVDALLSAQPKGDPRIEYQFFEDRHSAIKLRPKEGETYFDVVAVVDPVTREAQRLAPLLLVLAQLINMNLRVFMNCQSKLSDMPLKSFYRYVLEPEISFTSDNSFAKGPIAKFLDMPQSPLFTLNLNTPESWMVESVRTPYDLDNIYLEEVDSVVAAEYELEYLLLEGHCYDITTGQPPRGLQFTLGTSANPVIVDTIVMANLGYFQLKANPGAWILRLRKGRSEDIYRIYSHDGTDSPPDADEVVIVLNNFKSKIIKVKVQKKADMVNEDLLSDGTSENESGFWDSFKWGFTGQKTEEVKQDKDDIINIFSVASGHLYERFLRIMMLSVLKNTKTPVKFWFLKNYLSPTFKEFIPYMANEYNFQYELVQYKWPRWLHQQTEKQRIIWGYKILFLDVLFPLVVDKFLFVDADQIVRTDLKELRDFNLDGAPYGYTPFCDSRREMDGYRFWKSGYWASHLAGRKYHISALYVVDLKKFRKIAAGDRLRGQYQGLSQDPNSLSNLDQDLPNNMIHQVPIKSLPQEWLWCETWCDDASKKRAKTIDLCNNPMTKEPKLEAAVRIVPEWQDYDQEIKQLQIRFQKEKETGALYKEKTKEPSREGPQKREEL
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9NYU2 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y96 | Phosphorylation | Uniprot | |
| Y98 | Phosphorylation | Uniprot | |
| Y99 | Phosphorylation | Uniprot | |
| K157 | Ubiquitination | Uniprot | |
| K217 | Ubiquitination | Uniprot | |
| Y240 | Phosphorylation | Uniprot | |
| Y244 | Phosphorylation | Uniprot | |
| T253 | Phosphorylation | Uniprot | |
| Y255 | Phosphorylation | Uniprot | |
| S337 | Phosphorylation | Uniprot | |
| K356 | Ubiquitination | Uniprot | |
| K362 | Ubiquitination | Uniprot | |
| K378 | Acetylation | Uniprot | |
| K378 | Ubiquitination | Uniprot | |
| S445 | Phosphorylation | Uniprot | |
| Y449 | Phosphorylation | Uniprot | |
| S538 | Phosphorylation | Uniprot | |
| Y565 | Phosphorylation | Uniprot | |
| T580 | Phosphorylation | Uniprot | |
| Y684 | Phosphorylation | Uniprot | |
| Y741 | Phosphorylation | Uniprot | |
| S748 | Phosphorylation | Uniprot | |
| Y779 | Phosphorylation | Uniprot | |
| K930 | Ubiquitination | Uniprot | |
| S955 | Phosphorylation | Uniprot | |
| K959 | Ubiquitination | Uniprot | |
| Y966 | Phosphorylation | Uniprot | |
| R972 | Methylation | Uniprot | |
| S1026 | Phosphorylation | Uniprot | |
| K1034 | Acetylation | Uniprot | |
| R1038 | Methylation | Uniprot | |
| T1145 | Phosphorylation | Uniprot | |
| T1241 | O-Glycosylation | Uniprot | |
| S1277 | Phosphorylation | Uniprot | |
| T1282 | Phosphorylation | Uniprot | |
| K1287 | Ubiquitination | Uniprot | |
| S1296 | Phosphorylation | Uniprot | |
| R1435 | Methylation | Uniprot | |
| Y1516 | Phosphorylation | Uniprot |
研究背景
Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.
Endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment.
Higher levels in pancreas, skeletal muscle, kidney, and brain. Low levels in lung and heart.
Monomer as well as in a tight complex with SELENOF. Interacts with METTL23.
The N-terminal non-catalytic domain is assumed to mediate recognition of proteins with partial folding defects.
Belongs to the glycosyltransferase 8 family.
研究領域
· Genetic Information Processing > Folding, sorting and degradation > Protein processing in endoplasmic reticulum. (View pathway)
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