SSR1 Antibody - #DF8244
| 製品: | SSR1 Antibody |
| カタログ: | DF8244 |
| タンパク質の説明: | Rabbit polyclonal antibody to SSR1 |
| アプリケーション: | WB |
| 反応性: | Human |
| 予測: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 32 kDa; 32kD(Calculated). |
| ユニプロット: | P43307 |
| RRID: | AB_2841539 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF8244, RRID:AB_2841539.
折りたたみ／展開
DKFZp781N23103; FLJ14232; FLJ22100; FLJ23034; FLJ78242; FLJ93042; PGP35; Signal sequence receptor alpha; Signal sequence receptor alpha subunit; Signal sequence receptor subunit alpha; SSR 1; SSR alpha; SSR-alpha; SSR1; SSRA_HUMAN; SSRalpha; Translocon associated protein alpha; Translocon associated protein alpha subunit; Translocon associated protein subunit alpha; Translocon-associated protein subunit alpha; TRAP a; TRAP-alpha; TRAPa; TRAPalpha;
免疫原
- P43307 SSRA_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRLLPRLLLLLLLVFPATVLFRGGPRGLLAVAQDLTEDEETVEDSIIEDEDDEAEVEEDEPTDLVEDKEEEDVSGEPEASPSADTTILFVKGEDFPANNIVKFLVGFTNKGTEDFIVESLDASFRYPQDYQFYIQNFTALPLNTVVPPQRQATFEYSFIPAEPMGGRPFGLVINLNYKDLNGNVFQDAVFNQTVTVIEREDGLDGETIFMYMFLAGLGLLVIVGLHQLLESRKRKRPIQKVEMGTSSQNDVDMSWIPQETLNQINKASPRRLPRKRAQKRSVGSDE
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P43307 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S80 | Phosphorylation | Uniprot | |
| K91 | Ubiquitination | Uniprot | |
| K102 | Ubiquitination | Uniprot | |
| K110 | Ubiquitination | Uniprot | |
| N136 | N-Glycosylation | Uniprot | |
| Y156 | Phosphorylation | Uniprot | |
| N191 | N-Glycosylation | Uniprot | |
| T245 | Phosphorylation | Uniprot | |
| S246 | Phosphorylation | Uniprot | |
| S247 | Phosphorylation | Uniprot | |
| S254 | Phosphorylation | Uniprot | |
| T260 | Phosphorylation | Uniprot | |
| K266 | Ubiquitination | Uniprot | |
| S268 | Phosphorylation | P06493 (CDK1) | Uniprot |
| S281 | Phosphorylation | Uniprot | |
| S284 | Phosphorylation | Uniprot |
研究背景
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.
Endoplasmic reticulum membrane>Single-pass type I membrane protein.
Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma. Interacts with palmitoylated calnexin (CALX), the interaction is required for efficient folding of glycosylated proteins.
Shows a remarkable charge distribution with the N-terminus being highly negatively charged, and the cytoplasmic C-terminus positively charged.
Belongs to the TRAP-alpha family.
研究領域
· Genetic Information Processing > Folding, sorting and degradation > Protein processing in endoplasmic reticulum. (View pathway)
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