HYOU1 Antibody - #DF8329
| 製品: | HYOU1 Antibody |
| カタログ: | DF8329 |
| タンパク質の説明: | Rabbit polyclonal antibody to HYOU1 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Monkey |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 111 kDa; 111kD(Calculated). |
| ユニプロット: | Q9Y4L1 |
| RRID: | AB_2841601 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF8329, RRID:AB_2841601.
折りたたみ／展開
150 kDa oxygen regulated protein; 150 kDa oxygen-regulated protein; 170 kDa glucose regulated protein; 170 kDa glucose-regulated protein; DKFZp686N08236; FLJ94899; FLJ97572; glucose regulated protein 170; Grp 170; GRP-170; Grp170; HSP 12A; HSP12A; Hyou1; HYOU1_HUMAN; Hypoxia up regulated 1; hypoxia up-regulated 1 precursor; Hypoxia up-regulated protein 1; Hypoxia upregulated 1; Orp 150; ORP-150; Orp150; oxygen regulated protein (150kD);
免疫原
Highly expressed in tissues that contain well-developed endoplasmic reticulum and synthesize large amounts of secretory proteins. Highly expressed in liver and pancreas and lower expression in brain and kidney. Also expressed in macrophages within aortic atherosclerotic plaques, and in breast cancers.
- Q9Y4L1 HYOU1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDKSEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSVQKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAASTWLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGARLIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDREVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKVETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9Y4L1 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K51 | Ubiquitination | Uniprot | |
| K62 | Ubiquitination | Uniprot | |
| K75 | Ubiquitination | Uniprot | |
| R79 | Methylation | Uniprot | |
| K91 | Ubiquitination | Uniprot | |
| K94 | Ubiquitination | Uniprot | |
| K106 | Ubiquitination | Uniprot | |
| Y116 | Phosphorylation | Uniprot | |
| N155 | N-Glycosylation | Uniprot | |
| K198 | Acetylation | Uniprot | |
| K198 | Ubiquitination | Uniprot | |
| Y213 | Phosphorylation | Uniprot | |
| R262 | Methylation | Uniprot | |
| T269 | Phosphorylation | Uniprot | |
| R278 | Methylation | Uniprot | |
| K308 | Ubiquitination | Uniprot | |
| K398 | Ubiquitination | Uniprot | |
| K402 | Ubiquitination | Uniprot | |
| Y421 | Phosphorylation | Uniprot | |
| K433 | Ubiquitination | Uniprot | |
| Y443 | Phosphorylation | Uniprot | |
| K463 | Acetylation | Uniprot | |
| K463 | Ubiquitination | Uniprot | |
| N515 | N-Glycosylation | Uniprot | |
| K522 | Ubiquitination | Uniprot | |
| S527 | Phosphorylation | Uniprot | |
| K529 | Ubiquitination | Uniprot | |
| K537 | Ubiquitination | Uniprot | |
| S567 | Phosphorylation | Uniprot | |
| T580 | O-Glycosylation | Uniprot | |
| T589 | O-Glycosylation | Uniprot | |
| T590 | O-Glycosylation | Uniprot | |
| T590 | Phosphorylation | Uniprot | |
| N596 | N-Glycosylation | Uniprot | |
| T600 | Phosphorylation | Uniprot | |
| S634 | Phosphorylation | Uniprot | |
| T727 | Phosphorylation | Uniprot | |
| K738 | Ubiquitination | Uniprot | |
| S742 | Phosphorylation | Uniprot | |
| K753 | Ubiquitination | Uniprot | |
| Y759 | Phosphorylation | Uniprot | |
| S763 | Phosphorylation | Uniprot | |
| N830 | N-Glycosylation | Uniprot | |
| T850 | Phosphorylation | Uniprot | |
| N862 | N-Glycosylation | Uniprot | |
| N869 | N-Glycosylation | Uniprot | |
| R900 | Methylation | Uniprot | |
| Y904 | Phosphorylation | Uniprot | |
| N931 | N-Glycosylation | Uniprot | |
| T948 | Phosphorylation | Uniprot | |
| S955 | Phosphorylation | Uniprot |
研究背景
Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding.
Endoplasmic reticulum lumen.
Highly expressed in tissues that contain well-developed endoplasmic reticulum and synthesize large amounts of secretory proteins. Highly expressed in liver and pancreas and lower expression in brain and kidney. Also expressed in macrophages within aortic atherosclerotic plaques, and in breast cancers.
Part of a large chaperone multiprotein complex comprising DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PDIA6, PPIB, SDF2L1, UGT1A1 and very small amounts of ERP29, but not, or at very low levels, CALR nor CANX.
Belongs to the heat shock protein 70 family.
研究領域
· Genetic Information Processing > Folding, sorting and degradation > Protein processing in endoplasmic reticulum. (View pathway)
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