NOG Antibody - #DF8333
| 製品: | NOG Antibody |
| カタログ: | DF8333 |
| タンパク質の説明: | Rabbit polyclonal antibody to NOG |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Rat |
| 予測: | Bovine, Sheep, Dog |
| 分子量: | 26 kDa; 26kD(Calculated). |
| ユニプロット: | Q13253 |
| RRID: | AB_2841604 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF8333, RRID:AB_2841604.
折りたたみ／展開
Nog; NOGG_HUMAN; Noggin; SYM 1; SYM1; Symphalangism 1 (proximal); Synostoses (multiple) syndrome 1; SYNS 1; SYNS1;
免疫原
- Q13253 NOGG_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MERCPSLGVTLYALVVVLGLRATPAGGQHYLHIRPAPSDNLPLVDLIEHPDPIFDPKEKDLNETLLRSLLGGHYDPGFMATSPPEDRPGGGGGAAGGAEDLAELDQLLRQRPSGAMPSEIKGLEFSEGLAQGKKQRLSKKLRRKLQMWLWSQTFCPVLYAWNDLGSRFWPRYVKVGSCFSKRSCSVPEGMVCKPSKSVHLTVLRWRCQRRGGQRCGWIPIQYPIISECKCSC
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q13253 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y172 | Phosphorylation | Uniprot |
研究背景
Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. Essential for cartilage morphogenesis and joint formation. Inhibits chondrocyte differentiation through its interaction with GDF5 and, probably, GDF6.
Secreted.
Homodimer. Interacts with GDF5; inhibits chondrocyte differentiation.
Belongs to the noggin family.
研究領域
· Environmental Information Processing > Signal transduction > TGF-beta signaling pathway. (View pathway)
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