FCAR Antibody - #DF8356
| 製品: | FCAR Antibody |
| カタログ: | DF8356 |
| タンパク質の説明: | Rabbit polyclonal antibody to FCAR |
| アプリケーション: | WB |
| 反応性: | Human |
| 分子量: | 60 kDa; 32kD(Calculated). |
| ユニプロット: | P24071 |
| RRID: | AB_2841621 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF8356, RRID:AB_2841621.
折りたたみ／展開
CD89; Fc alpha receptor; Fc fragment of IgA, receptor for; FCAR; FCAR_HUMAN; IgA Fc receptor; Immunoglobulin alpha Fc receptor;
免疫原
Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages; however only one isoform is expressed at alveolar macrophages surfaces.
- P24071 FCAR_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDPKQTTLLCLVLCLGQRIQAQEGDFPMPFISAKSSPVIPLDGSVKIQCQAIREAYLTQLMIIKNSTYREIGRRLKFWNETDPEFVIDHMDANKAGRYQCQYRIGHYRFRYSDTLELVVTGLYGKPFLSADRGLVLMPGENISLTCSSAHIPFDRFSLAKEGELSLPQHQSGEHPANFSLGPVDLNVSGIYRCYGWYNRSPYLWSFPSNALELVVTDSIHQDYTTQNLIRMAVAGLVLVALLAILVENWHSHTALNKEASADVAEPSWSQQMCQPGLTFARTPSVCK
PTMs - P24071 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y56 | Phosphorylation | Uniprot | |
| N141 | N-Glycosylation | Uniprot | |
| N177 | N-Glycosylation | Uniprot |
研究背景
Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production.
Cell membrane>Single-pass type I membrane protein.
Cell membrane>Single-pass type I membrane protein.
Cell membrane>Single-pass type I membrane protein.
Secreted.
Secreted.
Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages; however only one isoform is expressed at alveolar macrophages surfaces.
Associates with the Fc epsilon RI gamma 2 receptor inducing tyrosine phosphorylation of gamma 2.
(Microbial infection) Interacts with Staphylococcus aureus protein SSL11.
研究領域
· Cellular Processes > Transport and catabolism > Phagosome. (View pathway)
· Human Diseases > Infectious diseases: Bacterial > Staphylococcus aureus infection.
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