SSB Antibody - #DF8417
| 製品: | SSB Antibody |
| カタログ: | DF8417 |
| タンパク質の説明: | Rabbit polyclonal antibody to SSB |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse |
| 予測: | Pig, Bovine, Horse, Sheep, Dog |
| 分子量: | 46 kDa; 47kD(Calculated). |
| ユニプロット: | P05455 |
| RRID: | AB_2841666 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF8417, RRID:AB_2841666.
折りたたみ／展開
Autoantigen La; La; La autoantigen; La autoantigen homolog; La protein; La ribonucleoprotein; La ribonucleoprotein domain family member 3; LA_HUMAN; LARP3; Lupus La antigen; Lupus La protein; Lupus La protein homolog; MGC118101; MGC93380; mRNA for autoantigen; OTTMUSP00000014043; RP23 273G23.1; Sjoegren syndrome type B antigen; Sjogren syndrome antigen B (autoantigen La); Sjogren syndrome antigen B; SS B; SS-B; SS-B/La protein; SSB;
免疫原
- P05455 LA_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAENGDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLEIMIKFNRLNRLTTDFNVIVEALSKSKAELMEISEDKTKIRRSPSKPLPEVTDEYKNDVKNRSVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLHKAFKGSIFVVFDSIESAKKFVETPGQKYKETDLLILFKDDYFAKKNEERKQNKVEAKLRAKQEQEAKQKLEEDAEMKSLEEKIGCLLKFSGDLDDQTCREDLHILFSNHGEIKWIDFVRGAKEGIILFKEKAKEALGKAKDANNGNLQLRNKEVTWEVLEGEVEKEALKKIIEDQQESLNKWKSKGRRFKGKGKGNKAAQPGSGKGKVQFQGKKTKFASDDEHDEHDENGATGPVKRAREETDKEEPASKQQKTENGAGDQ
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P05455 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K9 | Ubiquitination | Uniprot | |
| Y23 | Phosphorylation | Uniprot | |
| Y24 | Phosphorylation | Uniprot | |
| K37 | Ubiquitination | Uniprot | |
| K41 | Sumoylation | Uniprot | |
| K41 | Ubiquitination | Uniprot | |
| K74 | Ubiquitination | Uniprot | |
| K76 | Ubiquitination | Uniprot | |
| S83 | Phosphorylation | Uniprot | |
| K86 | Sumoylation | Uniprot | |
| K86 | Ubiquitination | Uniprot | |
| S92 | Phosphorylation | Uniprot | |
| S94 | Phosphorylation | Uniprot | |
| K95 | Acetylation | Uniprot | |
| K95 | Ubiquitination | Uniprot | |
| Y104 | Phosphorylation | Uniprot | |
| K105 | Ubiquitination | Uniprot | |
| K116 | Acetylation | Uniprot | |
| K116 | Ubiquitination | Uniprot | |
| T120 | Phosphorylation | Uniprot | |
| K128 | Acetylation | Uniprot | |
| K128 | Ubiquitination | Uniprot | |
| K165 | Acetylation | Uniprot | |
| K166 | Ubiquitination | Uniprot | |
| K174 | Ubiquitination | Uniprot | |
| K176 | Ubiquitination | Uniprot | |
| T178 | Phosphorylation | Uniprot | |
| K185 | Acetylation | Uniprot | |
| K185 | Sumoylation | Uniprot | |
| Y188 | Phosphorylation | Uniprot | |
| K191 | Methylation | Uniprot | |
| K200 | Sumoylation | Uniprot | |
| K208 | Sumoylation | Uniprot | |
| K208 | Ubiquitination | Uniprot | |
| K216 | Acetylation | Uniprot | |
| K216 | Ubiquitination | Uniprot | |
| K224 | Ubiquitination | Uniprot | |
| S225 | Phosphorylation | Uniprot | |
| K229 | Ubiquitination | Uniprot | |
| C232 | S-Nitrosylation | Uniprot | |
| K235 | Ubiquitination | Uniprot | |
| R266 | Methylation | Uniprot | |
| K269 | Ubiquitination | Uniprot | |
| K276 | Ubiquitination | Uniprot | |
| K280 | Acetylation | Uniprot | |
| K285 | Acetylation | Uniprot | |
| K287 | Ubiquitination | Uniprot | |
| K299 | Ubiquitination | Uniprot | |
| T302 | Phosphorylation | P31749 (AKT1) | Uniprot |
| K312 | Ubiquitination | Uniprot | |
| S325 | Phosphorylation | Uniprot | |
| K328 | Acetylation | Uniprot | |
| K328 | Ubiquitination | Uniprot | |
| K352 | Acetylation | Uniprot | |
| K352 | Ubiquitination | Uniprot | |
| K354 | Acetylation | Uniprot | |
| K354 | Ubiquitination | Uniprot | |
| K360 | Acetylation | Uniprot | |
| K361 | Acetylation | Uniprot | |
| T362 | Phosphorylation | Uniprot | |
| S366 | Phosphorylation | P68400 (CSNK2A1) | Uniprot |
| T379 | Phosphorylation | Uniprot | |
| T389 | Phosphorylation | Uniprot | |
| K391 | Acetylation | Uniprot | |
| K397 | Ubiquitination | Uniprot |
研究背景
Binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation. In case of Coxsackievirus B3 infection, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation.
Phosphorylated. The phosphorylation sites are at the C-terminal part of the protein.
The N-terminus is blocked.
Nucleus.
Interacts with DDX15. May interact with RUFY1.
研究領域
· Human Diseases > Immune diseases > Systemic lupus erythematosus.
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