RAE1 Antibody - #DF8442
| 製品: | RAE1 Antibody |
| カタログ: | DF8442 |
| タンパク質の説明: | Rabbit polyclonal antibody to RAE1 |
| アプリケーション: | WB IHC |
| 反応性: | Human |
| 予測: | Pig, Zebrafish, Bovine, Horse, Sheep, Dog, Chicken, Xenopus |
| 分子量: | 41 kDa; 41kD(Calculated). |
| ユニプロット: | P78406 |
| RRID: | AB_2841686 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF8442, RRID:AB_2841686.
折りたたみ／展開
dJ481F12.3; dJ800J21.1; FLJ30608; Homolog of yeast Rae1 (Bharathi) mRNA associated protein of 41 kDa (Kraemer); Homolog of yeast Rae1 mRNA associated protein of 41 kDa; MGC117333; MGC126076; MGC126077; MIG 14; MIG14; Migration inducing gene 14; Mnrp 41; Mnrp41; mRNA associated protein mrnp 41; mRNA binding protein 41 kD; mRNA export factor; mRNA export protein; mRNA-associated protein mrnp 41; MRNP 41; MRNP41; RAE 1; RAE1 (RNA export 1 S.pombe) homolog; rae1; RAE1 homolog; Rae1 protein homolog; RAE1 RNA export 1 homolog (S. pombe); RAE1 RNA export 1 homolog; RAE1L_HUMAN; RNA export 1; RNA export 1 homolog;
免疫原
- P78406 RAE1L_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSLFGTTSGFGTSGTSMFGSATTDNHNPMKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAGSWANDVRCWEVQDSGQTIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLSSNQAIQIAQHDAPVKTIHWIKAPNYSCVMTGSWDKTLKFWDTRSSNPMMVLQLPERCYCADVIYPMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRVAIHYINPPNPAKDNFTFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSFWDKDARTKLKTSEQLDQPISACCFNHNGNIFAYASSYDWSKGHEFYNPQKKNYIFLRNAAEELKPRNKK
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P78406 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T12 | Phosphorylation | Uniprot | |
| K80 | Ubiquitination | Uniprot | |
| K100 | Ubiquitination | Uniprot | |
| K108 | Acetylation | Uniprot | |
| K108 | Ubiquitination | Uniprot | |
| K111 | Ubiquitination | Uniprot | |
| K131 | Acetylation | Uniprot | |
| K131 | Ubiquitination | Uniprot | |
| K151 | Ubiquitination | Uniprot | |
| K154 | Ubiquitination | Uniprot | |
| S160 | Phosphorylation | Uniprot | |
| Y180 | Phosphorylation | Uniprot | |
| S209 | Phosphorylation | Uniprot | |
| K212 | Methylation | Uniprot | |
| K212 | Ubiquitination | Uniprot | |
| K222 | Ubiquitination | Uniprot | |
| K224 | Ubiquitination | Uniprot | |
| K227 | Ubiquitination | Uniprot | |
| T229 | Phosphorylation | Uniprot | |
| K252 | Acetylation | Uniprot | |
| K252 | Ubiquitination | Uniprot | |
| K258 | Methylation | Uniprot | |
| K258 | Ubiquitination | Uniprot | |
| Y274 | Phosphorylation | Uniprot | |
| K302 | Ubiquitination | Uniprot | |
| K309 | Ubiquitination | Uniprot | |
| Y345 | Phosphorylation | Uniprot | |
| K349 | Ubiquitination | Uniprot | |
| K350 | Ubiquitination | Uniprot | |
| R356 | Methylation | Uniprot | |
| K363 | Ubiquitination | Uniprot |
研究背景
Plays a role in mitotic bipolar spindle formation. Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton.
Cytoplasm. Nucleus. Cytoplasm>Cytoskeleton>Spindle pole.
Note: Recruited from interphase nuclei to spindle MTs during mitosis.
Interacts with NUMA1 (via N-terminal end of the coiled-coil domain); this interaction promotes spindle formation in mitosis. Interacts with NUP98. Interacts with MYCBP2.
Belongs to the WD repeat rae1 family.
研究領域
· Genetic Information Processing > Translation > RNA transport.
· Human Diseases > Infectious diseases: Viral > Influenza A.
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