ARF5 Antibody - #DF8451
| 製品: | ARF5 Antibody |
| カタログ: | DF8451 |
| タンパク質の説明: | Rabbit polyclonal antibody to ARF5 |
| アプリケーション: | WB IHC |
| 反応性: | Human |
| 予測: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Chicken |
| 分子量: | 20 kDa; 21kD(Calculated). |
| ユニプロット: | P84085 |
| RRID: | AB_2841691 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF8451, RRID:AB_2841691.
折りたたみ／展開
ADP ribosylation factor 5; ADP-ribosylation factor 5; ARF 5; Arf5; ARF5_HUMAN;
免疫原
- P84085 ARF5_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAVLLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHELSKR
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P84085 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| G2 | Myristoylation | Uniprot | |
| T4 | Phosphorylation | Uniprot | |
| S6 | Phosphorylation | Uniprot | |
| S10 | Phosphorylation | Uniprot | |
| Y35 | Phosphorylation | Uniprot | |
| K36 | Acetylation | Uniprot | |
| K36 | Ubiquitination | Uniprot | |
| K38 | Ubiquitination | Uniprot | |
| Y58 | Phosphorylation | Uniprot | |
| K73 | Sumoylation | Uniprot | |
| S103 | Phosphorylation | Uniprot | |
| R117 | Methylation | Uniprot | |
| K127 | Ubiquitination | Uniprot | |
| S137 | Phosphorylation | Uniprot | |
| T140 | Phosphorylation | Uniprot | |
| K142 | Ubiquitination | Uniprot | |
| C159 | S-Nitrosylation | Uniprot |
研究背景
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
(Microbial infection) Functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase.
Golgi apparatus. Cytoplasm>Perinuclear region. Membrane>Lipid-anchor. Golgi apparatus>trans-Golgi network membrane>Lipid-anchor.
Interacts (when activated) with GGA1, GGA2 and GGA3; the interaction is required for proper subcellular location of GGA1, GGA2 and GGA3. Binds ASAP2. Interacts with NCS1/FREQ at the Golgi complex. Interacts with RAB11FIP3 and RAB11FIP4.
Belongs to the small GTPase superfamily. Arf family.
研究領域
· Cellular Processes > Transport and catabolism > Endocytosis. (View pathway)
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