GSR Antibody - #DF8471
| 製品: | GSR Antibody |
| カタログ: | DF8471 |
| タンパク質の説明: | Rabbit polyclonal antibody to GSR |
| アプリケーション: | WB IHC |
| 反応性: | Human, Rat |
| 予測: | Bovine, Horse, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 56 kDa; 56kD(Calculated). |
| ユニプロット: | P00390 |
| RRID: | AB_2841703 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF8471, RRID:AB_2841703.
折りたたみ／展開
GLR1; GLUR; Glutathione reductase; Glutathione reductase mitochondrial; Glutathione reductase, mitochondrial; GR; Gr1; GRase; GRD 1; GRD1; GSHR_HUMAN; GSR; MGC78522;
免疫原
- P00390 GSHR_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MALLPRALSAGAGPSWRRAARAFRGFLLLLPEPAALTRALSRAMACRQEPQPQGPPPAAGAVASYDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPKKVMWNTAVHSEFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDPKPTIEVSGKKYTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELPGRSVIVGAGYIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQVKEVKKTLSGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVDEFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P00390 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y65 | Phosphorylation | Uniprot | |
| K97 | Acetylation | Uniprot | |
| K97 | Ubiquitination | Uniprot | |
| C107 | S-Nitrosylation | Uniprot | |
| K110 | Acetylation | Uniprot | |
| Y158 | Phosphorylation | Uniprot | |
| K164 | Acetylation | Uniprot | |
| K164 | Ubiquitination | Uniprot | |
| K181 | Ubiquitination | Uniprot | |
| K189 | Acetylation | Uniprot | |
| K189 | Ubiquitination | Uniprot | |
| K190 | Acetylation | Uniprot | |
| C278 | S-Nitrosylation | Uniprot | |
| K291 | Ubiquitination | Uniprot | |
| K296 | Ubiquitination | Uniprot | |
| K300 | Ubiquitination | Uniprot | |
| T301 | Phosphorylation | Uniprot | |
| S308 | Phosphorylation | Uniprot | |
| K340 | Ubiquitination | Uniprot | |
| K346 | Ubiquitination | Uniprot | |
| K354 | Ubiquitination | Uniprot | |
| K368 | Ubiquitination | Uniprot | |
| Y371 | Phosphorylation | Uniprot | |
| C377 | S-Nitrosylation | Uniprot | |
| K379 | Ubiquitination | Uniprot | |
| T383 | Phosphorylation | Uniprot | |
| K401 | Acetylation | Uniprot | |
| K401 | Ubiquitination | Uniprot | |
| K405 | Ubiquitination | Uniprot | |
| Y408 | Phosphorylation | Uniprot | |
| T427 | Phosphorylation | Uniprot | |
| K434 | Ubiquitination | Uniprot | |
| K441 | Ubiquitination | Uniprot | |
| S446 | Phosphorylation | Uniprot | |
| T448 | Phosphorylation | Uniprot | |
| Y451 | Phosphorylation | Uniprot | |
| T455 | Phosphorylation | Uniprot | |
| K456 | Acetylation | Uniprot | |
| K456 | Ubiquitination | Uniprot | |
| K464 | Ubiquitination | Uniprot | |
| K470 | Acetylation | Uniprot | |
| K470 | Ubiquitination | Uniprot | |
| C484 | S-Nitrosylation | Uniprot | |
| K501 | Ubiquitination | Uniprot | |
| T507 | Phosphorylation | Uniprot | |
| T513 | Phosphorylation | Uniprot | |
| S514 | Phosphorylation | Uniprot | |
| S515 | Phosphorylation | Uniprot | |
| R522 | Methylation | Uniprot |
研究背景
Maintains high levels of reduced glutathione in the cytosol.
Mitochondrion.
Cytoplasm.
Homodimer; disulfide-linked.
Each subunit can be divided into 4 domains that are consecutive along the polypeptide chain. Domains 1 and 2 bind FAD and NADPH, respectively. Domain 4 forms the interface.
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
研究領域
· Metabolism > Metabolism of other amino acids > Glutathione metabolism.
· Organismal Systems > Endocrine system > Thyroid hormone synthesis.
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