TACR2 Antibody - #DF8472
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF8472, RRID:AB_2841704.
折りたたみ／展開
Neurokinin 2 receptor; Neurokinin A receptor; NK 2 receptor; NK 2R; NK-2 receptor; NK-2R; NK2 receptor; NK2R; NK2R_HUMAN; NKNAR; Seven transmembrane helix receptor; SKR; Substance K receptor; Substance-K receptor; TAC 2R; TAC R2; TAC2R; Tachykinin receptor 2 (substance K receptor; neurokinin 2 receptor); Tachykinin receptor 2; TACR 2; TACR2;
免疫原
- P21452 NK2R_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGTCDIVTEANISSGPESNTTGITAFSMPSWQLALWATAYLALVLVAVTGNAIVIWIILAHRRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQPRLSAPSTKAVIAGIWLVALALASPQCFYSTVTMDQGATKCVVAWPEDSGGKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHGANLRHLQAMKKFVKTMVLVVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTKEDKLELTPTTSLSTRVNRCHTKETLFMAGDTAPSEATSGEAGRPQDGSGLWFGYGLLAPTKTHVEI
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P21452 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y132 | Phosphorylation | Uniprot | |
| S147 | Phosphorylation | Uniprot | |
| T148 | Phosphorylation | Uniprot | |
| T339 | Phosphorylation | Uniprot |
研究背景
This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P.
Cell membrane>Multi-pass membrane protein.
Belongs to the G-protein coupled receptor 1 family.
研究領域
· Environmental Information Processing > Signal transduction > Calcium signaling pathway. (View pathway)
· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.
Restrictive clause
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