製品: Cathepsin H Antibody
カタログ: DF8514
タンパク質の説明: Rabbit polyclonal antibody to Cathepsin H
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse
予測: Pig, Bovine, Horse, Sheep, Rabbit, Dog
分子量: 37kDa,25kDa; 37kD(Calculated).
ユニプロット: P09668
RRID: AB_2841719

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
予測:
Pig(88%), Bovine(100%), Horse(88%), Sheep(100%), Rabbit(100%), Dog(88%)
クローナリティ:
Polyclonal
特異性:
Cathepsin H Antibody detects endogenous levels of total Cathepsin H.
RRID:
AB_2841719
引用形式: Affinity Biosciences Cat# DF8514, RRID:AB_2841719.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

ACC 4; ACC 5; ACC4; ACC5; aleurain; CATH_HUMAN; cathepsin B3; cathepsin BA; Cathepsin H heavy chain; Cathepsin H light chain; Cathepsin H mini chain; CPSB; CTSH; minichain; N benzoylarginine beta naphthylamide hydrolase; N-benzoylarginine-beta-naphthylamide hydrolase; pro cathepsin H;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MWATLPLLCAGAWLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFASNWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPYPPSVDWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACASYPIPLV

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Bovine
100
Sheep
100
Rabbit
100
Pig
88
Horse
88
Dog
88
Chicken
63
Xenopus
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P09668 基板として

Site PTM Type Enzyme
Y94 Phosphorylation
N101 N-Glycosylation
S103 Phosphorylation
K106 Ubiquitination
C141 S-Nitrosylation
T204 Phosphorylation
Y205 Phosphorylation
N230 N-Glycosylation

研究背景

機能:

Important for the overall degradation of proteins in lysosomes.

細胞の位置付け:

Lysosome.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Composed of a mini chain and a large chain. The large chain may be split into heavy and light chain. All chains are held together by disulfide bonds.

タンパク質ファミリー:

Belongs to the peptidase C1 family.

研究領域

· Cellular Processes > Transport and catabolism > Lysosome.   (View pathway)

· Cellular Processes > Cell growth and death > Apoptosis.   (View pathway)

Restrictive clause

 

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