Endo G Antibody - #DF8541
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| 製品: | Endo G Antibody |
| カタログ: | DF8541 |
| タンパク質の説明: | Rabbit polyclonal antibody to Endo G |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Sheep |
| 分子量: | 32 kDa; 33kD(Calculated). |
| ユニプロット: | Q14249 |
| RRID: | AB_2841745 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF8541, RRID:AB_2841745.
折りたたみ／展開
EndoG; Endonuclease G; Endonuclease G mitochondrial; EndonucleaseG; FLJ27463; Mitochondrial endonuclease G; NUCG_HUMAN;
免疫原
- Q14249 NUCG_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRALRAGLTLASGAGLGAVVEGWRRRREDARAAPGLLGRLPVLPVAAAAELPPVPGGPRGPGELAKYGLPGLAQLKSRESYVLCYDPRTRGALWVVEQLRPERLRGDGDRRECDFREDDSVHAYHRATNADYRGSGFDRGHLAAAANHRWSQKAMDDTFYLSNVAPQVPHLNQNAWNNLEKYSRSLTRSYQNVYVCTGPLFLPRTEADGKSYVKYQVIGKNHVAVPTHFFKVLILEAAGGQIELRTYVMPNAPVDEAIPLERFLVPIESIERASGLLFVPNILARAGSLKAITAGSK
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q14249 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T9 | Phosphorylation | Uniprot | |
| S12 | Phosphorylation | Uniprot | |
| K66 | Ubiquitination | Uniprot | |
| K76 | Ubiquitination | Uniprot | |
| K153 | Ubiquitination | Uniprot | |
| K181 | Ubiquitination | Uniprot | |
| K210 | Ubiquitination | Uniprot | |
| K214 | Ubiquitination | Uniprot | |
| K220 | Ubiquitination | Uniprot | |
| K290 | Ubiquitination | Uniprot |
研究背景
Cleaves DNA at double-stranded (DG)n.(DC)n and at single-stranded (DC)n tracts. In addition to deoxyribonuclease activities, also has ribonuclease (RNase) and RNase H activities. Capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA (By similarity).
Mitochondrion.
Homodimer.
Belongs to the DNA/RNA non-specific endonuclease family.
研究領域
· Cellular Processes > Cell growth and death > Apoptosis. (View pathway)
参考文献
Application: WB Species: human Sample: LS174T cells
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